Atomic force microscope investigation of large-circle DNA molecules
文献类型：期刊论文
| 作者 | Wu AG ; Yu LH ; Li ZA ; Yang HM ; Wang EK |
| 刊名 | analytical biochemistry
 |
| 出版日期 | 2004 |
| 卷号 | 325期号:2页码:293-300 |
| 关键词 | CARBON NANOTUBE PROBES HIGH-RESOLUTION PLASMID DNA SUPERCOILED DNA LONG DNA SURFACES MICA POLYMERASE DEPOSITION FLOW |
| ISSN号 | 0003-2697 |
| 通讯作者 | li za |
| 中文摘要 | a circular bacterial artificial chromosome of 148.9 kbp on human chromosome 3 has been extended and fixed on bare mica substrates using a developed fluid capillary flow method in evaporating liquid drops. extended circular dna molecules were imaged with an atomic force microscope (afm) under ambient conditions. the measured total lengths of the whole dna molecules were in agreement with sequencing analysis data with an error range of +/-3.6%. this work is important groundwork for probing single nucleotide polymorphisms in the human genome, mapping genomic dna, manipulating biomolecular nanotechnology, and studying the interaction of dna-protein complexes investigated by afm. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000188791200013 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/14825]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu AG,Yu LH,Li ZA,et al. Atomic force microscope investigation of large-circle DNA molecules[J]. analytical biochemistry,2004,325(2):293-300. |
| APA | Wu AG,Yu LH,Li ZA,Yang HM,&Wang EK.(2004).Atomic force microscope investigation of large-circle DNA molecules.analytical biochemistry,325(2),293-300. |
| MLA | Wu AG,et al."Atomic force microscope investigation of large-circle DNA molecules".analytical biochemistry 325.2(2004):293-300. |
入库方式： OAI收割
来源：长春应用化学研究所
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