A novel method to construct a third-generation biosensor: self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres
文献类型：期刊论文
| 作者 | Xu SY ; Han XZ |
| 刊名 | biosensors & bioelectronics
 |
| 出版日期 | 2004 |
| 卷号 | 19期号:9页码:1117-1120 |
| 关键词 | ELECTRODES MONOLAYER ELECTROCHEMISTRY MICROSPHERES RECOGNITION AFFINITY SURFACE AU |
| ISSN号 | 0956-5663 |
| 通讯作者 | han xz |
| 中文摘要 | a novel method for fabrication of horseradish peroxidase (hrp) biosensor has been developed by self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) (st-co-aa) nanospheres. at first, a cleaned gold electrode was immersed in thiol-functionalized poly(st-co-aa) nanosphere latex prepared by emulsifier-free emulsion polymerization of st with aa and function with dithioglycol to assemble the nanospheres, then gold nanoparticles were chemisorbed onto the thiol groups. finally, horseradish peroxi- dase was immobilized on the surface of the gold nanoparticles. the sensor displayed an excellent electrocatalytical response to reduction of h2o2 without the aid of an electron mediator. the sensor was highly sensitive to hydrogen peroxide with a detection limit of 4.0 mumol l(-1), and the linear range was from 10.0 mumol l(-1) to 7.0 mmol l(-1). the biosensor retained more than 97.8% of its original activity after 60 days of use. moreover, the studied biosensor exhibited good current repeatability and good fabrication reproducibility. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000220276100019 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/15445]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Xu SY,Han XZ. A novel method to construct a third-generation biosensor: self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres[J]. biosensors & bioelectronics,2004,19(9):1117-1120. |
| APA | Xu SY,&Han XZ.(2004).A novel method to construct a third-generation biosensor: self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres.biosensors & bioelectronics,19(9),1117-1120. |
| MLA | Xu SY,et al."A novel method to construct a third-generation biosensor: self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres".biosensors & bioelectronics 19.9(2004):1117-1120. |
入库方式： OAI收割
来源：长春应用化学研究所
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