Structural elucidation and identification of alkaloids in Rhizoma Coptidis by electrospray ionization tandem mass spectrometry
文献类型：期刊论文
| 作者 | Wang DW ; Liu ZQ ; Guo MQ ; Liu SY |
| 刊名 | journal of mass spectrometry
 |
| 出版日期 | 2004 |
| 卷号 | 39期号:11页码:1356-1365 |
| 关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY CRUDE DRUGS CAPILLARY-ELECTROPHORESIS QUATERNARY ALKALOIDS MICROSCOPIC ANALYSIS PHELLODENDRI CORTEX ION-TRAP BERBERINE CONSTITUENTS PALMATINE |
| ISSN号 | 1076-5174 |
| 通讯作者 | liu sy |
| 中文摘要 | simple, convenient, sensitive and accurate analytical methods are needed for the structural characterization and identification of alkaloid components in rhizoma coptidis in traditional chinese herbal medicine, which has important bioactivity. in this work, the identification of alkaloid compounds in rhizoma coptidis was investigated by obtaining molecular mass information using electrospray ionization mass spectrometry (esi-ms). multi-stage tandem mass spectrometric (esi-msn) data for the alkaloid compounds were used for detailed structural characterization, then structure information was obtained by comparison of the fragmentation mechanisms of both alkaloids in rhizoma coptidis and standard samples of berberine, palmatine, coptisine and jatrorrhizine by ms. based on the results obtained, the structure of a novel compound was elucidated. the results of the experiments demonstrate that esi-msn is a sensitive, selective and effective tool for the rapid determination of alkaloids in rhizoma coptidis. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000225339000012 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://202.98.16.49/handle/322003/15453]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang DW,Liu ZQ,Guo MQ,et al. Structural elucidation and identification of alkaloids in Rhizoma Coptidis by electrospray ionization tandem mass spectrometry[J]. journal of mass spectrometry,2004,39(11):1356-1365. |
| APA | Wang DW,Liu ZQ,Guo MQ,&Liu SY.(2004).Structural elucidation and identification of alkaloids in Rhizoma Coptidis by electrospray ionization tandem mass spectrometry.journal of mass spectrometry,39(11),1356-1365. |
| MLA | Wang DW,et al."Structural elucidation and identification of alkaloids in Rhizoma Coptidis by electrospray ionization tandem mass spectrometry".journal of mass spectrometry 39.11(2004):1356-1365. |
入库方式： OAI收割
来源：长春应用化学研究所
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