The complex kinetics of protein folding in wide temperature ranges
文献类型:期刊论文
作者 | Wang J |
刊名 | biophysical journal
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出版日期 | 2004 |
卷号 | 87期号:4页码:2164-2171 |
关键词 | RANDOM-ENERGY-MODEL MOLECULE ENZYMATIC DYNAMICS SINGLE-MOLECULE TRANSITION-STATE LANDSCAPE THEORY HETEROPOLYMERS PATHWAYS INTERMITTENCY COOPERATIVITY SPECTROSCOPY |
ISSN号 | 0006-3495 |
通讯作者 | wang j |
中文摘要 | the complex protein folding kinetics in wide temperature ranges is studied through diffusive dynamics on the underlying energy landscape. the well-known kinetic chevron rollover behavior is recovered from the mean first passage time, with the u-shape dependence on temperature. the fastest folding temperature t-0 is found to be smaller than the folding transition temperature t-f. we found that the fluctuations of the kinetics through the distribution of first passage time show rather universal behavior, from high-temperature exponential poissonian kinetics to the relatively low-temperature highly nonexponential kinetics. the transition temperature is at t-k and t-0, t-k, t-f. in certain low-temperature regimes, a power law behavior at long time emerges. at very low temperatures ( lower than trapping transition temperature t< t-0/(4∼6)), the kinetics is an exponential poissonian process again. |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000224129200006 |
公开日期 | 2010-08-17 |
源URL | [http://202.98.16.49/handle/322003/15627] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Wang J. The complex kinetics of protein folding in wide temperature ranges[J]. biophysical journal,2004,87(4):2164-2171. |
APA | Wang J.(2004).The complex kinetics of protein folding in wide temperature ranges.biophysical journal,87(4),2164-2171. |
MLA | Wang J."The complex kinetics of protein folding in wide temperature ranges".biophysical journal 87.4(2004):2164-2171. |
入库方式: OAI收割
来源:长春应用化学研究所
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