NMR and pattern recognition studies on the acute biochemical effects of Lu(NO3)(3)
文献类型：期刊论文
| 作者 | Wu HF ; Zhang XY ; Feng JH ; Sun GY ; Wu YJ ; Pei FK ; Nie YX |
| 刊名 | chinese journal of chemistry
 |
| 出版日期 | 2004 |
| 卷号 | 22期号:8页码:849-853 |
| 关键词 | MAGNETIC-RESONANCE SPECTROSCOPY URINE RAT CLASSIFICATION NEPHROTOXICITY LESIONS SPECTRA |
| ISSN号 | 1001-604x |
| 通讯作者 | wu hf |
| 中文摘要 | pattern recognition methods were applied to the analysis of 600 mhz h-1 nmr spectra of urine from rats dosed with compounds that induced organ-specific damage in the liver and kidney. male wistar rats were separated into groups (n=4) and each was treated with one of following compounds: hgcl2, ccl4, lu(no3)(3) and changle (a kind of rare earth complex mixed with la, ce, pr and nd). urine samples from the rats dosed with hgcl2, ccl4 and lu(no3)(3) were collected over a 24 h time course and the samples from the rats administrated with changle were gained after 3 months. these samples were measured by 600 mhz nmr spectroscopy. each spectrum was data-processed to provide 223 intensity-related descriptors of spectra. urine spectral data corresponding to the time intervals, 0-8 h (hgcl2 and ccl4), 4-8 (lu(no3)(3)) h and 90 d (changle) were analyzed using principal component analysis (pca). successful classification of the toxicity and biochemical effects of lu(no3)(3) was achieved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000223452500016 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/15653]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu HF,Zhang XY,Feng JH,et al. NMR and pattern recognition studies on the acute biochemical effects of Lu(NO3)(3)[J]. chinese journal of chemistry,2004,22(8):849-853. |
| APA | Wu HF.,Zhang XY.,Feng JH.,Sun GY.,Wu YJ.,...&Nie YX.(2004).NMR and pattern recognition studies on the acute biochemical effects of Lu(NO3)(3).chinese journal of chemistry,22(8),849-853. |
| MLA | Wu HF,et al."NMR and pattern recognition studies on the acute biochemical effects of Lu(NO3)(3)".chinese journal of chemistry 22.8(2004):849-853. |
入库方式： OAI收割
来源：长春应用化学研究所
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