Enzymatic degradation of poly(L-lactide) and poly (epsilon-caprolactone) electrospun fibers
文献类型：期刊论文
| 作者 | Zeng J ; Chen XS ; Liang QZ ; Xu XL ; Jing XB |
| 刊名 | macromolecular bioscience
 |
| 出版日期 | 2004 |
| 卷号 | 4期号:12页码:1118-1125 |
| 关键词 | POLY(LACTIC ACID) CRYSTALLINITY BIODEGRADATION MORPHOLOGY STEREOCOPOLYMERS STEREOCHEMISTRY NANOFIBERS MEMBRANES BLEND |
| ISSN号 | 1616-5187 |
| 通讯作者 | jing xb |
| 中文摘要 | poly(l-lactide) (plla) and poly(epsilon-caprolactone) (pcl) ultrafine fibers were prepared by electrospinning. the influence of cationic and anionic surfactants on their enzymatic degradation behavior was investigated by measuring weight loss, molecular weight, crystallinity, and melting temperature of the fibers as a function of degradation time. under the catalysis of proteinase k, the plla fibers containing the anionic surfactant sodium docecyl sulfate (sds) exhibited a faster degradation rate than those containing cationic surfactant triethylbenzylammonium chloride (tebac), indicating that surface electric charge on the fibers is a critical factor for an enzymatic degradation. similarly, tebac-containing pcl fibers exhibited a 47% weight loss within 8.5 h whereas sds-containing pcl fibers showed little degradation in the presence of lipase ps. by analyzing the charge status of proteinase k and lipase ps under the experimental conditions, the importance of the surface charges of the fibers and their interactions with the charges on the enzymes were revealed. consequently, a "two-step" degradation mechanism was proposed: (1) the enzyme approaches the fiber surface; (2) the enzyme initiates hydrolysis of the polymer. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000227008100006 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/15701]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zeng J,Chen XS,Liang QZ,et al. Enzymatic degradation of poly(L-lactide) and poly (epsilon-caprolactone) electrospun fibers[J]. macromolecular bioscience,2004,4(12):1118-1125. |
| APA | Zeng J,Chen XS,Liang QZ,Xu XL,&Jing XB.(2004).Enzymatic degradation of poly(L-lactide) and poly (epsilon-caprolactone) electrospun fibers.macromolecular bioscience,4(12),1118-1125. |
| MLA | Zeng J,et al."Enzymatic degradation of poly(L-lactide) and poly (epsilon-caprolactone) electrospun fibers".macromolecular bioscience 4.12(2004):1118-1125. |
入库方式： OAI收割
来源：长春应用化学研究所
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