Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers
文献类型：期刊论文
| 作者 | Yu HJ ; Wang WS ; Chen XS ; Deng C ; Jing XB |
| 刊名 | biopolymers
 |
| 出版日期 | 2006 |
| 卷号 | 83期号:3页码:233-242 |
| 关键词 | CHEMICAL-MODIFICATIONS DERIVATIVES ACID POLYSACCHARIDE TRANSFECTION HYDROGELS DELIVERY |
| ISSN号 | 0006-3525 |
| 通讯作者 | jing xb |
| 中文摘要 | a novel synthetic approach to biodegradable amphiphilic copolymers based on poly (epsilon-caprolactone) (pcl) and chitosan was presented, and the prepared copolymers were used to prepare nanoparticles successfully. the pcl-graft-chitosan copolymers were synthesized by coupling the hydroxyl end-groups on preformed pcl chains and the amino groups present on 6-o-triphenylmethyl chitosan and by removing the protective 6-o-triphenylmethyl groups in acidic aqueous solution. the pcl content in the copolymers can be controlled in the range of 10-90 wt %. the graft copolymers were thoroughly characterized by h-1 nam, c-13 nmr, ft-ir and dsc. the nanoparticles made from the graft copolymers were investigated by h-1 nmr, dls, afm and sem measurements. it was found that the copolymers could form spherical or elliptic nanoparticles it? water. the amount of available primary amines on the surface of the prepared nanoparticles was evaluated by ninhydrin assail, and it can be controlled by the grafting degree of pcl. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000240709800004 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/16273]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yu HJ,Wang WS,Chen XS,et al. Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers[J]. biopolymers,2006,83(3):233-242. |
| APA | Yu HJ,Wang WS,Chen XS,Deng C,&Jing XB.(2006).Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers.biopolymers,83(3),233-242. |
| MLA | Yu HJ,et al."Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers".biopolymers 83.3(2006):233-242. |
入库方式： OAI收割
来源：长春应用化学研究所
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