A study on the interaction between ibuprofen and bilayer lipid membrane
文献类型：期刊论文
| 作者 | Du LW ; Liu XH ; Huang Wm ; Wang EK |
| 刊名 | electrochimica acta
 |
| 出版日期 | 2006 |
| 卷号 | 51期号:26页码:5754-5760 |
| 关键词 | GLASSY-CARBON ELECTRODES ION-CHANNEL BEHAVIOR CYCLIC VOLTAMMETRY CHARGE-TRANSFER AC-IMPEDANCE FILMS ELECTROCHEMISTRY PHOSPHOLIPIDS PERMEABILITY ASSOCIATION |
| ISSN号 | 0013-4686 |
| 通讯作者 | wang ek |
| 中文摘要 | ibuprofen is a well-known nonsteroidal anti-inflammatory drug, which can interact with lipid membranes. in this paper, the interaction of ibuprofen with bilayer lipid membrane was studied by uv-vis spectroscopy, cyclic voltammetry and ac impedance spectroscopy. uv-vis spectroscopy data indicated directly that ibuprofen could interact with lipid vesicles. in electrochemical experiments, ibuprofen displayed a biphasic behavior on bilayer lipid membrane supported on a glassy carbon electrode. it could stabilize the lipid membrane in low concentration, while it induced defects formation, even removed off bilayer lipid membrane from the surface of the electrode with increasing concentration. the mechanism about the interaction between ibuprofen and supported bilayer lipid membrane was discussed. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000240167400024 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/16297]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Du LW,Liu XH,Huang Wm,et al. A study on the interaction between ibuprofen and bilayer lipid membrane[J]. electrochimica acta,2006,51(26):5754-5760. |
| APA | Du LW,Liu XH,Huang Wm,&Wang EK.(2006).A study on the interaction between ibuprofen and bilayer lipid membrane.electrochimica acta,51(26),5754-5760. |
| MLA | Du LW,et al."A study on the interaction between ibuprofen and bilayer lipid membrane".electrochimica acta 51.26(2006):5754-5760. |
入库方式： OAI收割
来源：长春应用化学研究所
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