Determination of ranitidine in urine by capillary electrophoresis-electrochemiluminescent detection
文献类型：期刊论文
| 作者 | Gao Y ; Tian YL ; Sun XH ; Yin XB ; Xiang Q ; Ma G ; Wang EK |
| 刊名 | journal of chromatography b-analytical technologies in the biomedical and life sciences
 |
| 出版日期 | 2006 |
| 卷号 | 832期号:2页码:236-240 |
| 关键词 | SOLID-PHASE EXTRACTION PHARMACEUTICAL FORMULATIONS BIOLOGICAL-FLUIDS HUMAN SERUM PLASMA CHROMATOGRAPHY METABOLITES FAMOTIDINE NIZATIDINE CIMETIDINE |
| ISSN号 | 1570-0232 |
| 通讯作者 | wang ek |
| 中文摘要 | the fast analysis of ranitidine is of clinical importance in understanding its efficiency and a patient's treatment history. in this paper, a novel determination method for ranitidine based on capillary electrophoresis-electrochemiluminescence detection is described. the conditions affecting separation and detection were investigated in detail. end-column detection of ranitidine in 5 mm ru(bpy)(3)(2+) solution at applied voltage of 1.20 v was performed. favorable ecl intensity with higher column efficiency was achieved by electrokinetic injection for 10 s at 10 kv. the r.s.d. values of ecl intensity and migration time were 6.38 and 1.84% for 10(-4) m and 6.01 and 0.60% for 10(-5) m, respectively. a detection limit of 7 x 10(-8) m (s/n = 3) was achieved. the proposed method was applied satisfactorily to the determination of ranitidine in urine in 6 min. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000236291800011 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/16319]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Gao Y,Tian YL,Sun XH,et al. Determination of ranitidine in urine by capillary electrophoresis-electrochemiluminescent detection[J]. journal of chromatography b-analytical technologies in the biomedical and life sciences,2006,832(2):236-240. |
| APA | Gao Y.,Tian YL.,Sun XH.,Yin XB.,Xiang Q.,...&Wang EK.(2006).Determination of ranitidine in urine by capillary electrophoresis-electrochemiluminescent detection.journal of chromatography b-analytical technologies in the biomedical and life sciences,832(2),236-240. |
| MLA | Gao Y,et al."Determination of ranitidine in urine by capillary electrophoresis-electrochemiluminescent detection".journal of chromatography b-analytical technologies in the biomedical and life sciences 832.2(2006):236-240. |
入库方式： OAI收割
来源：长春应用化学研究所
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