Comparison of biochemical effects induced by Changle between male and female rats using NMR and ICP-MS techniques
文献类型：期刊论文
| 作者 | Wu HF ; Li XJ ; Feng JH ; Li WS ; Li ZF ; Liao PQ ; Wu YJ ; Pei FK |
| 刊名 | journal of rare earths
 |
| 出版日期 | 2006 |
| 卷号 | 24期号:1页码:108-114 |
| 关键词 | MAGNETIC-RESONANCE SPECTROSCOPY PATTERN-RECOGNITION METHODS H-1-NMR SPECTROSCOPY URINE CLASSIFICATION METABOLITES IDENTIFICATION NEPHROTOXICITY SPECTRA LESIONS |
| ISSN号 | 1002-0721 |
| 通讯作者 | pei fk |
| 中文摘要 | metabolic profiles caused by rare earth complex were investigated using nmr and icp-ms techniques. male and female wistar rats were treated orally with changle (a kind of rare earth complex applied in agriculture to raise the production of crops) at dose of 2, 5 and 20 mg (.) kg(-1) body weight/day respectively for 90 d. urine and serum samples are collected on 90 d. the relative concentrations of important endogenous metabolites in urine and serum are determined from h-1 nmr spectra and the contents of the four rare earth elements ( la, ce, pr and nd) constituting changle in the serum samples are measured by icp-ms technique. changle-induced renal and liver damage in rats is found based on the increase in the amounts of the amino acids, trimethylamine n-oxide, n, n-dimethyglycine, dimethylamine, succinate, aketoglutarate and ethanol as well as rare earth concentrations. the similarities and differentiations are found in the alteration patterns of metabolites and rare earth concentrations in serum. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000236434100021 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/16967]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu HF,Li XJ,Feng JH,et al. Comparison of biochemical effects induced by Changle between male and female rats using NMR and ICP-MS techniques[J]. journal of rare earths,2006,24(1):108-114. |
| APA | Wu HF.,Li XJ.,Feng JH.,Li WS.,Li ZF.,...&Pei FK.(2006).Comparison of biochemical effects induced by Changle between male and female rats using NMR and ICP-MS techniques.journal of rare earths,24(1),108-114. |
| MLA | Wu HF,et al."Comparison of biochemical effects induced by Changle between male and female rats using NMR and ICP-MS techniques".journal of rare earths 24.1(2006):108-114. |
入库方式： OAI收割
来源：长春应用化学研究所
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