Surface modification of poly(L-lactic acid) to improve its cytocompatibility via assembly of polyelectrolytes and gelatin
文献类型：期刊论文
| 作者 | Lin Y ; Wang LL ; Zhang PB ; Wang X ; Chen XS ; Jing XB ; Su ZH |
| 刊名 | acta biomaterialia
 |
| 出版日期 | 2006 |
| 卷号 | 2期号:2页码:155-164 |
| 关键词 | HUMAN ENDOTHELIAL-CELLS BY-LAYER DEPOSITION BIODEGRADABLE POLYMERS LIVER-CELLS IMMOBILIZATION SCAFFOLD ADSORPTION COLLAGEN MEMBRANE PROTEIN |
| ISSN号 | 1742-7061 |
| 通讯作者 | su zh |
| 中文摘要 | poly(l-lactide) (plla) surface was modified via aminolysis by poly(allylamine hydrochloride) (pah) at high ph and subsequent electrostatic self-assembly of poly(sodium styrenesulfonate) (pss) and pah, and the process was monitored by x-ray photoelectron spectroscopy (xps) and contact angle measurement. these modified pllas were then used as charged substrates for further incorporation of gelatin to improve their cytocompatibility. the amphoteric nature of the gelatin was exploited and the gelatin was adsorbed to the negatively charged plla/pss and positively charged plla/pah at ph = 3.4 and 7.4, respectively. xps and water contact angle data indicated that the gelatin adsorption at ph = 3.4 resulted in much higher surface coverage by gelatin than at ph = 7.4. all the modified plla surfaces became more hydrophilic than the virgin plla. chondrocyte culture was used to test the cell attachment, cell morphology and cell viability on the modified plla substrates. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000235787700003 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/16989]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Lin Y,Wang LL,Zhang PB,et al. Surface modification of poly(L-lactic acid) to improve its cytocompatibility via assembly of polyelectrolytes and gelatin[J]. acta biomaterialia,2006,2(2):155-164. |
| APA | Lin Y.,Wang LL.,Zhang PB.,Wang X.,Chen XS.,...&Su ZH.(2006).Surface modification of poly(L-lactic acid) to improve its cytocompatibility via assembly of polyelectrolytes and gelatin.acta biomaterialia,2(2),155-164. |
| MLA | Lin Y,et al."Surface modification of poly(L-lactic acid) to improve its cytocompatibility via assembly of polyelectrolytes and gelatin".acta biomaterialia 2.2(2006):155-164. |
入库方式： OAI收割
来源：长春应用化学研究所
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