Determination of diphenhydramine by capillary electrophoresis with tris(2,2 '-bipyridyl)ruthenium(II) electrochemiluminescence detection
文献类型：期刊论文
| 作者 | Liu JF ; Cao WD ; Yang XR ; Wang EK |
| 刊名 | talanta
 |
| 出版日期 | 2003 |
| 卷号 | 59期号:3页码:453-459 |
| 关键词 | RU(BPY)(3)(3+)-BASED CHEMILUMINESCENCE DETECTION ELECTROGENERATED CHEMILUMINESCENCE ELECTROKINETIC CHROMATOGRAPHY LIQUID-CHROMATOGRAPHY GAS-CHROMATOGRAPHY FLOW-INJECTION AMINO-ACIDS N-OXIDE HYDROCHLORIDE LUMINESCENCE |
| ISSN号 | 0039-9140 |
| 通讯作者 | wang ek |
| 中文摘要 | tris(2,2'-bipyridyl)ruthenium(ii) electrochemiluminescence detection in a capillary electrophoresis separation system was used for the determination of diphenhydramine. in this study, platinum disk electrode (300 mum in diameter) was used as a working electrode and the influence of applied potential and buffer conditions were investigated. under optimal conditions: 1.2 v applied potential, ph 8.50, 15 kv separation voltage and 10 mmol l(-1) running buffer, the calibration curve of diphenhydramine was linear over the range of 4 x 10(-8) to 1 x 10(-5) mol l(-1). this technique gave satisfactory precision, and relative standard deviations of migration times and chemiluminescence peak intensities were less than 1 and 6%, respectively. the technique was applied to animal studies for determination of diphenhydramine extracted from rabbit plasma and urine samples, and the extraction efficiency were between 92 and 98.5%. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000182199000004 |
| 公开日期 | 2010-09-13 |
| 源URL | [http://202.98.16.49/handle/322003/17533]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Liu JF,Cao WD,Yang XR,et al. Determination of diphenhydramine by capillary electrophoresis with tris(2,2 '-bipyridyl)ruthenium(II) electrochemiluminescence detection[J]. talanta,2003,59(3):453-459. |
| APA | Liu JF,Cao WD,Yang XR,&Wang EK.(2003).Determination of diphenhydramine by capillary electrophoresis with tris(2,2 '-bipyridyl)ruthenium(II) electrochemiluminescence detection.talanta,59(3),453-459. |
| MLA | Liu JF,et al."Determination of diphenhydramine by capillary electrophoresis with tris(2,2 '-bipyridyl)ruthenium(II) electrochemiluminescence detection".talanta 59.3(2003):453-459. |
入库方式： OAI收割
来源：长春应用化学研究所
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