Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green
文献类型：期刊论文
| 作者 | Huang WM ; Zhang ZL ; Han XJ ; Tang JL ; Wang JG ; Dong SJ ; Wang EK |
| 刊名 | bioelectrochemistry
 |
| 出版日期 | 2003 |
| 卷号 | 59期号:1-2页码:21-27 |
| ISSN号 | 1567-5394 |
| 关键词 | CARBON-PASTE ELECTRODES ADSORPTIVE STRIPPING POTENTIOMETRY CALF THYMUS DNA TRACE MEASUREMENTS NUCLEIC-ACIDS B-DNA COMPLEXES OXIDATION BINDING RNA |
| 通讯作者 | dong sj |
| 中文摘要 | recent studies have focused on the structural features of dna-lipid assemblies. in this paper, we take methyl green (mg) as a probe molecule to detect the conformational change of dna molecule induced by dimethyldioctadecylammonium bromide (ddab) liposomes before the condensation process of dna begins. ddab-induced dna topology changes were investigated by cyclic voltammetry (cv), circular dichroism (cd) and uv-vis spectrometry. we find that upon binding to dna, positively charged liposomes induce a conformational transition of dna molecules from the native b-form to the c motif. conformational transition in dna results in the binding modes of mg to dna, changing and being isolated from dna to the solution. more stable complexes are formed between dna and ddab. that is also proved by the melting study of dna. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000183052800003 |
| 公开日期 | 2010-09-13 |
| 源URL | [http://202.98.16.49/handle/322003/17535]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Huang WM,Zhang ZL,Han XJ,et al. Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green[J]. bioelectrochemistry,2003,59(1-2):21-27. |
| APA | Huang WM.,Zhang ZL.,Han XJ.,Tang JL.,Wang JG.,...&Wang EK.(2003).Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green.bioelectrochemistry,59(1-2),21-27. |
| MLA | Huang WM,et al."Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green".bioelectrochemistry 59.1-2(2003):21-27. |
入库方式： OAI收割
来源：长春应用化学研究所
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