Energy landscape theory, funnels, specificity, and optimal criterion of biomolecular binding
文献类型：期刊论文
| 作者 | Wang J ; Verkhivker GM |
| 刊名 | physical review letters
 |
| 出版日期 | 2003 |
| 卷号 | 90期号:18页码:文献编号：188101 |
| 关键词 | MOLECULAR RECOGNITION STATISTICAL-MECHANICS FOLDING FUNNELS MODEL DISCOVERY |
| ISSN号 | 0031-9007 |
| 通讯作者 | wang j |
| 中文摘要 | we study the nature of biomolecular binding. we found that in general there exists several thermodynamic phases: a native binding phase, a non-native phase, and a glass or local trapping phase. the quantitative optimal criterion for the binding specificity is found to be the maximization of the ratio of the binding transition temperature versus the trapping transition temperature, or equivalently the ratio of the energy gap of binding between the native state and the average non-native states versus the dispersion or variance of the non-native states. this leads to a funneled binding energy landscape. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000182823900052 |
| 公开日期 | 2010-09-13 |
| 源URL | [http://202.98.16.49/handle/322003/17929]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang J,Verkhivker GM. Energy landscape theory, funnels, specificity, and optimal criterion of biomolecular binding[J]. physical review letters,2003,90(18):文献编号：188101. |
| APA | Wang J,&Verkhivker GM.(2003).Energy landscape theory, funnels, specificity, and optimal criterion of biomolecular binding.physical review letters,90(18),文献编号：188101. |
| MLA | Wang J,et al."Energy landscape theory, funnels, specificity, and optimal criterion of biomolecular binding".physical review letters 90.18(2003):文献编号：188101. |
入库方式： OAI收割
来源：长春应用化学研究所
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