The structural transition of DNA-Tris(1,10-phenanthroline) cobalt(III) complexes in ethanol-water solution
文献类型：期刊论文
| 作者 | Zheng JP ; Li Z ; Wu AG ; Zhou HL ; Bai HY ; Song YH |
| 刊名 | biochemical and biophysical research communications
 |
| 出版日期 | 2002 |
| 卷号 | 299期号:5页码:910-915 |
| 关键词 | SCANNING FORCE MICROSCOPY TRIS-CHELATED COMPLEXES DNA CONDENSATION BINDING MODE CLEAVAGE HELICES TOROIDS ASSAY ACID DRUG |
| ISSN号 | 0006-291x |
| 通讯作者 | li z |
| 中文摘要 | the interaction of dna with tris(1,10-phenanthroline) cobalt(iii) was studied by means of atomic force microscopy. changes in the morphologies of dna complex in the presence of ethanol may well indicate the crucial role of electrostatic force in causing dna condensation. with the increase of the concentration of ethanol, electrostatic interaction is enhanced corresponding to a lower dielectric constant. counterions condense along the sugar phosphate backbone of dna when e is lowered and the phosphate charge density can thus be neutralized to the level of dna condensation. electroanalytical measurement of dna condensed with co(phen)(3)(3+) in ethanol solution indicated that intercalating reaction remains existing. according to both the microscopic and spectroscopic results, it can be found that no secondary structure transition occurs upon dna condensing. b-a conformation transition takes place at more than 60% ethanol solution. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000180886900036 |
| 公开日期 | 2010-11-03 |
| 源URL | [http://202.98.16.49/handle/322003/18123]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zheng JP,Li Z,Wu AG,et al. The structural transition of DNA-Tris(1,10-phenanthroline) cobalt(III) complexes in ethanol-water solution[J]. biochemical and biophysical research communications,2002,299(5):910-915. |
| APA | Zheng JP,Li Z,Wu AG,Zhou HL,Bai HY,&Song YH.(2002).The structural transition of DNA-Tris(1,10-phenanthroline) cobalt(III) complexes in ethanol-water solution.biochemical and biophysical research communications,299(5),910-915. |
| MLA | Zheng JP,et al."The structural transition of DNA-Tris(1,10-phenanthroline) cobalt(III) complexes in ethanol-water solution".biochemical and biophysical research communications 299.5(2002):910-915. |
入库方式： OAI收割
来源：长春应用化学研究所
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