Effect of rare earth element on the metabolism in rats by high resolution proton nuclear magnetic resonance spectroscopy
文献类型：期刊论文
| 作者 | Li XJ ; Feng JH ; Zhang SR ; Pei FK ; Chen X ; Nie YX |
| 刊名 | chinese journal of analytical chemistry
 |
| 出版日期 | 2000 |
| 卷号 | 28期号:12页码:1472-1475 |
| ISSN号 | 0253-3820 |
| 通讯作者 | pei fk |
| 中文摘要 | the high-field nuclear magnetic resonance (nmr) spectra can be used for the rapid multicomponent analysis in small amounts of biological fluids. in this paper, the effect of la (no3)(3) on the rats' metabolism in urine was investigated by h-1 nmr analysis. the experimental groups of wistar rats were injected intraperitoneally with la(no3)(3) at doses of 0.2, 2.0, 10 and 20mg/kg body weight. the remarkable variation of low molecular weight metabolites in urine has been identified by h-1 nmr spectra, in which dimethylamine, n, n-dimethylglycine, urea, alpha -ketoglutarate, trimethylamine n-oxide, succinate, citrate and amino acids have been suggested as nmr markers for renal damage and ethanol, lactate, taurine as the markers for liver damage. this work may assess its possible use in the early detection of biochemical changes associated with rare earth induced kidney and liver dysfunction. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 中文 |
| WOS记录号 | WOS:000166075300005 |
| 公开日期 | 2010-11-04 |
| 源URL | [http://202.98.16.49/handle/322003/19417]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li XJ,Feng JH,Zhang SR,et al. Effect of rare earth element on the metabolism in rats by high resolution proton nuclear magnetic resonance spectroscopy[J]. chinese journal of analytical chemistry,2000,28(12):1472-1475. |
| APA | Li XJ,Feng JH,Zhang SR,Pei FK,Chen X,&Nie YX.(2000).Effect of rare earth element on the metabolism in rats by high resolution proton nuclear magnetic resonance spectroscopy.chinese journal of analytical chemistry,28(12),1472-1475. |
| MLA | Li XJ,et al."Effect of rare earth element on the metabolism in rats by high resolution proton nuclear magnetic resonance spectroscopy".chinese journal of analytical chemistry 28.12(2000):1472-1475. |
入库方式： OAI收割
来源：长春应用化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。