Effects of rare earth ions and calmodulin on the activity of lactate dehydrogenase
文献类型：期刊论文
| 作者 | Li WG ; Lu ZW ; Zhao DQ ; Ni JZ |
| 刊名 | chinese journal of inorganic chemistry
 |
| 出版日期 | 2001 |
| 卷号 | 17期号:6页码:843-848 |
| ISSN号 | 1001-4861 |
| 通讯作者 | zhao dq |
| 中文摘要 | in this paper, the effects of rare earth ions (la3+, eu3+, dy3+, yb3+) and their complexes with calmodulin on the activity of lactate dehydrogenase (ldh) were investigated. the results reveal that whether binding with calmodulin or not, rare earth ions show a minor activation effects on ldh when their concentrations are less than 3 mu mol (.) l-1, but indicate some strong inhibitory effects on ldh activity when the concentrations are above 5 mu mol (.) l-1. calmodulin, which is a calcium-dependent regulator, can stimulate ldh activity and release the inhibitory effects of rare earth ion. diethylenetriamine pentaacetic acid(dtpa) and its derivatives bisdimethylamide-diethylenetriamine pentaacetic acid (dtpa-bdma), bisisonicotinyl-diethylenetriamine pentaacetic acid (dtpa-bin), which are often used as ligands to metal ions, inhibit ldh activity when their concentrations are above 5 mu mol (.) l-1. calmodulin can also release their inhibitory effects at the same time. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 中文 |
| WOS记录号 | WOS:000172081500013 |
| 公开日期 | 2010-11-04 |
| 源URL | [http://202.98.16.49/handle/322003/20485]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li WG,Lu ZW,Zhao DQ,et al. Effects of rare earth ions and calmodulin on the activity of lactate dehydrogenase[J]. chinese journal of inorganic chemistry,2001,17(6):843-848. |
| APA | Li WG,Lu ZW,Zhao DQ,&Ni JZ.(2001).Effects of rare earth ions and calmodulin on the activity of lactate dehydrogenase.chinese journal of inorganic chemistry,17(6),843-848. |
| MLA | Li WG,et al."Effects of rare earth ions and calmodulin on the activity of lactate dehydrogenase".chinese journal of inorganic chemistry 17.6(2001):843-848. |
入库方式： OAI收割
来源：长春应用化学研究所
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