Bond-Selective Imaging of Cells by Mid-Infrared Photothermal Microscopy in High Wavenumber Region
文献类型：期刊论文
| 作者 | Liu, Cheng; Bai, Yeran; Zhang, Delong; Li, Chen; Cheng, Ji-Xin |
| 刊名 | J. Phys. Chem. B
 |
| 出版日期 | 2017 |
| 卷号 | 121期号:44页码:10249 |
| 通讯作者 | jxcheng@bu.edu |
| 英文摘要 | Using a visible beam to probe the thermal effect induced by infrared absorption, mid-infrared photothermal (MIP) microscopy allows bond-selective chemical imaging at submicron spatial resolution. Current MIP microscopes cannot reach the high wavenumber region due to the limited tunability of the existing quantum cascade laser source. We extend the spectral range of MIP microscopy by difference frequency generation (DFG) from two chirped femtosecond pulses. Flexible wavelength tuning in both C-D and C-H regions was achieved with mid-infrared power up to 22.1 mW and spectral width of 29.3 cm(-1). Distribution of fatty acid in live human lung cancer cells was revealed by MIP imaging of the C-D bond at 2192 cm(-1). |
| 收录类别 | SCI |
| 资助信息 | Keck Foundation Science and Engineering grant; UCAS Joint Ph.D. Training Program [UCAS [2015]37] |
| WOS记录号 | WOS:000415140000007 |
| 源URL | [http://ir.siom.ac.cn/handle/181231/27937]  |
| 专题 | 上海光学精密机械研究所_高功率激光物理国家实验室 |
| 作者单位 | 中国科学院上海光学精密机械研究所 |
| 推荐引用方式 GB/T 7714 | Liu, Cheng,Bai, Yeran,Zhang, Delong,et al. Bond-Selective Imaging of Cells by Mid-Infrared Photothermal Microscopy in High Wavenumber Region[J]. J. Phys. Chem. B,2017,121(44):10249. |
| APA | Liu, Cheng,Bai, Yeran,Zhang, Delong,Li, Chen,&Cheng, Ji-Xin.(2017).Bond-Selective Imaging of Cells by Mid-Infrared Photothermal Microscopy in High Wavenumber Region.J. Phys. Chem. B,121(44),10249. |
| MLA | Liu, Cheng,et al."Bond-Selective Imaging of Cells by Mid-Infrared Photothermal Microscopy in High Wavenumber Region".J. Phys. Chem. B 121.44(2017):10249. |
入库方式： OAI收割
来源：上海光学精密机械研究所
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