Preparation of two-photon fluorescent probe and biological imaging application in cells
文献类型：期刊论文
| 作者 | Chi SH(迟书恒); Li L(李亮); Wu YQ(吴谊群) |
| 刊名 | Chin. Opt. Lett.
 |
| 出版日期 | 2016 |
| 卷号 | 14期号:6 |
| 通讯作者 | yqwu@siom.ac.cn |
| 英文摘要 | We report on a novel dibenzothiophene-based two-photon fluorescent probe for selective nuclear bioimaging, which contains bilaterally symmetrical pyridine rings connected by a central conjugated-bridge dibenzothiophene. This probe possesses a large two-photon absorption cross-section of 471 GM, yields a 25-fold enhancement of the fluorescence titration, and a stronger photostability for nuclei labeling than existing probes. The real-time observation period is a minimum of 1800 s under a femtosecond laser excitation, which is significantly longer than that of 4',6-diamidino-2-phenylindole. The above results confirm that this novel molecule is a suitable two-photon fluorescent probe for application to nuclear bioimaging in cells. |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [61137002, 61178059, 51172253] |
| WOS记录号 | WOS:000378344500016 |
| 源URL | [http://ir.siom.ac.cn/handle/181231/28252]  |
| 专题 | 上海光学精密机械研究所_高密度光存储技术实验室 |
| 作者单位 | 中国科学院上海光学精密机械研究所 |
| 推荐引用方式 GB/T 7714 | Chi SH,Li L,Wu YQ. Preparation of two-photon fluorescent probe and biological imaging application in cells[J]. Chin. Opt. Lett.,2016,14(6). |
| APA | 迟书恒,李亮,&吴谊群.(2016).Preparation of two-photon fluorescent probe and biological imaging application in cells.Chin. Opt. Lett.,14(6). |
| MLA | 迟书恒,et al."Preparation of two-photon fluorescent probe and biological imaging application in cells".Chin. Opt. Lett. 14.6(2016). |
入库方式： OAI收割
来源：上海光学精密机械研究所
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