Separation of six xanthones from Swertia franchetiana by high-speed countercurrent chromatography
文献类型：期刊论文
| 作者 | Li, Hongmei1,2; Li, Yulin2; Wang, Weiqing3; Sun, Jing2; Chen, Tao2 |
| 刊名 | JOURNAL OF SEPARATION SCIENCE
 |
| 出版日期 | 2017-06-01 |
| 卷号 | 40期号:11页码:2515-2521 |
| 关键词 | countercurrent chromatography isomers Swertia franchetiana xanthones |
| 英文摘要 | In our present study, two groups of xanthones isomers (1-hydroxy-3,5,8-trimethoxyxanthone and 1-hydroxy-3,7,8-trimethoxyxanthone; 1,8-dihydroxy-3,7-dimethoxyxanthone and 1,8-dihydroxy-3,5-dimethanolxanthone) and other two xanthones (3-methoxy-1,5,8-trihydroxyxanthone and 3,5-dimethoxy-1-hydroxyxanthone) were separated from Swertia franchetiana. First, a solvent system composed of petroleum ether/methanol/water (2:1:0.6, v/v) was developed for the liquid-liquid extraction of these xanthones from the crude extract. Then, an efficient method was established for the one-step separation of these six xanthones by high-speed countercurrent chromatography using n-hexane/ethyl acetate/methanol/ethanol/water (HEMEW; 6:4:4:2:4, v/v) as the solvent system. The results showed that liquid-liquid extraction could be well developed for efficient enrichment of target compounds. Additionally, high-speed countercurrent chromatography could be a powerful technology for separation xanthones isomers. It was found ethanol could be a good methanol substitute when the HEMEW system could not provide good separation factors. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Analytical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | PERFORMANCE LIQUID-CHROMATOGRAPHY ; 3 ANTHRAQUINONE GLYCOSIDES ; RHEUM-TANGUTICUM ; ULTRAFILTRATION-HPLC ; MACROPOROUS RESIN ; RAPID ENRICHMENT ; PURIFICATION ; EXTRACTION ; IDENTIFICATION ; INHIBITORS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000403461500023 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/7085]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Univ Chinese Acad Sci, Savaid Med Sch, Beijing, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining, Peoples R China 3.Qinghai Prov Prod Qual Supervis & Inspect Ctr, Xining, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Hongmei,Li, Yulin,Wang, Weiqing,et al. Separation of six xanthones from Swertia franchetiana by high-speed countercurrent chromatography[J]. JOURNAL OF SEPARATION SCIENCE,2017,40(11):2515-2521. |
| APA | Li, Hongmei,Li, Yulin,Wang, Weiqing,Sun, Jing,&Chen, Tao.(2017).Separation of six xanthones from Swertia franchetiana by high-speed countercurrent chromatography.JOURNAL OF SEPARATION SCIENCE,40(11),2515-2521. |
| MLA | Li, Hongmei,et al."Separation of six xanthones from Swertia franchetiana by high-speed countercurrent chromatography".JOURNAL OF SEPARATION SCIENCE 40.11(2017):2515-2521. |
入库方式： OAI收割
来源：西北高原生物研究所
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