Generic synthesis and versatile applications of molecularly organic-inorganic hybrid mesoporous organosilica nanoparticles with asymmetric Janus topologies and structures
文献类型：期刊论文
| 作者 | Zhang, Jiamin; Tao, Guiju; Bai, Zhengyuan; Zhang, Long; Chen, Yu; Yao, Heliang; Wu, Meiying; Huang, Ping; Yu, Luodan; Dai, Chen |
| 刊名 | Nano Res.
 |
| 出版日期 | 2017 |
| 卷号 | 10期号:11页码:3790 |
| 通讯作者 | chenyu@mail.sic.ac.cn ; lzhang@siom.ac.cn |
| 英文摘要 | Precise control over the morphology, nanostructure, composition, and particle size of molecularly organic-inorganic hybrid mesoporous organosilica nanoparticles (MONs) still remains a major challenge, which severely restricts their broad applications. In this work, an efficient bridged organic group-determined growth strategy has been proposed for the facile synthesis of highly dispersed and uniform MONs with multifarious Janus morphologies, nanostructures, organic-inorganic hybrid compositions, and particle sizes, which can be easily controlled simply by varying the bridged organic groups and the concentration of bis-silylated organosilica precursors used in the synthesis. In addition, the formation mechanism of Janus MONs determined by the bridged organic group has been discussed. Based on the specific structures, compositions, and asymmetric morphologies, all the synthesized Janus MONs with hollow structures (JHMONs) demonstrate excellent performances in nanomedicine as desirable drug carriers with high drug-loading efficiencies/capacities, pH-responsive drug releasing, and enhanced therapeutic efficiencies, as attractive contrastenhanced contrast agents for ultrasound imaging, and as excellent bilirubin adsorbents with noticeably high adsorption capacities and high blood compatibilities. The developed versatile synthetic strategy and the obtained JHMONs are extremely important in the development and applications of MONs, particularly in the areas of nanoscience and nanotechnology. |
| 收录类别 | SCI |
| 资助信息 | National Key Research and Development Program of China [2016YFA0203700]; Shanghai Natural Science Foundation [16ZR1440300]; National Natural Science Foundation of China [61275208, 51302293, 51672303]; Shanghai Rising-Star Program [14QA1404100]; Youth Innovation Promotion Association of the Chinese Academy of Sciences [2013169]; Development Fund for Shanghai Talents |
| WOS记录号 | WOS:000413100400017 |
| 源URL | [http://ir.siom.ac.cn/handle/181231/28086]  |
| 专题 | 上海光学精密机械研究所_中科院强激光材料重点实验室 |
| 作者单位 | 中国科学院上海光学精密机械研究所 |
| 推荐引用方式 GB/T 7714 | Zhang, Jiamin,Tao, Guiju,Bai, Zhengyuan,et al. Generic synthesis and versatile applications of molecularly organic-inorganic hybrid mesoporous organosilica nanoparticles with asymmetric Janus topologies and structures[J]. Nano Res.,2017,10(11):3790. |
| APA | Zhang, Jiamin.,Tao, Guiju.,Bai, Zhengyuan.,Zhang, Long.,Chen, Yu.,...&Dai, Chen.(2017).Generic synthesis and versatile applications of molecularly organic-inorganic hybrid mesoporous organosilica nanoparticles with asymmetric Janus topologies and structures.Nano Res.,10(11),3790. |
| MLA | Zhang, Jiamin,et al."Generic synthesis and versatile applications of molecularly organic-inorganic hybrid mesoporous organosilica nanoparticles with asymmetric Janus topologies and structures".Nano Res. 10.11(2017):3790. |
入库方式： OAI收割
来源：上海光学精密机械研究所
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