High-sensitivity intravascular photoacoustic imaging of lipid-laden plaque with a collinear catheter design
文献类型：期刊论文
| 作者 | Yu, Qianhuan; Chen, Weibiao; Sturek, Michael; Cheng, Ji-Xin; Cao, Yingchun; Hui, Jie; Kole, Ayeeshik; Wang, Pu |
| 刊名 | Sci Rep
 |
| 出版日期 | 2016 |
| 卷号 | 6 |
| 通讯作者 | msturek@iupui.edu ; jcheng@purdue.edu |
| 英文摘要 | A highly sensitive catheter probe is critical to catheter-based intravascular photoacoustic imaging. Here, we present a photoacoustic catheter probe design on the basis of collinear alignment of the incident optical wave and the photoacoustically generated sound wave within a miniature catheter housing for the first time. Such collinear catheter design with an outer diameter of 1.6 mm provided highly efficient overlap between optical and acoustic waves over an imaging depth of >6 mm in D2O medium. Intravascular photoacoustic imaging of lipid-laden atherosclerotic plaque and perivascular fat was demonstrated, where a lab-built 500 Hz optical parametric oscillator outputting nanosecond optical pulses at a wavelength of 1.7 mu m was used for overtone excitation of C-H bonds. In addition to intravascular imaging, the presented catheter design will benefit other photoacoustic applications such as needle-based intramuscular imaging. |
| 收录类别 | SCI |
| 资助信息 | Center of Excellence in Cardiovascular Research Grant; AHA Postdoctoral Fellowship; IUPUI Graduate Imaging Research Fellowship; [R01HL125385] |
| WOS记录号 | WOS:000374949700002 |
| 源URL | [http://ir.siom.ac.cn/handle/181231/28389]  |
| 专题 | 上海光学精密机械研究所_空间激光信息技术研究中心 |
| 作者单位 | 中国科学院上海光学精密机械研究所 |
| 推荐引用方式 GB/T 7714 | Yu, Qianhuan,Chen, Weibiao,Sturek, Michael,et al. High-sensitivity intravascular photoacoustic imaging of lipid-laden plaque with a collinear catheter design[J]. Sci Rep,2016,6. |
| APA | Yu, Qianhuan.,Chen, Weibiao.,Sturek, Michael.,Cheng, Ji-Xin.,Cao, Yingchun.,...&Wang, Pu.(2016).High-sensitivity intravascular photoacoustic imaging of lipid-laden plaque with a collinear catheter design.Sci Rep,6. |
| MLA | Yu, Qianhuan,et al."High-sensitivity intravascular photoacoustic imaging of lipid-laden plaque with a collinear catheter design".Sci Rep 6(2016). |
入库方式： OAI收割
来源：上海光学精密机械研究所
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