Novel Tetrapeptide Hydrophilic Interaction Chromatography Materials for High. efficiency Glycopeptide Enrichment
文献类型：期刊论文
| 作者 | Li Xiu-Ling1; Chen Cheng1; Wang Hong-Xi2; Kang Hong-Jian1; Yao Yao2; Qing Guang-Yan2; Liang Xin-Miao1 |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2017-08-01 |
| 卷号 | 45期号:8页码:1149-1154 |
| 关键词 | Hydrophilic interaction chromatography Tetrapeptide Glycopeptide enrichment Mass spectrometry |
| 英文摘要 | In this study, a novel tetrapeptide hydrophilic interaction chromatography (HILIC) material was synthesized, and corresponding enrichment method for glycopeptides was developed. The tetrapeptide modified silica gel materials (denoted as Poly. DAPD) were synthesized by atom. transfer radical. polymerization (ATRP) and characterized by N-2 adsorption desorption and thermometer, thermal gravimetric analyzer (TGA) and X. ray photoelectron spectrometer (XPS). The characterization results indicated that tetrapeptide had been successfully synthesized on silica gel. Poly. DAPD materials showed high enrichment selectivity toward fetuin glycopeptides under solid. phase extraction (SPE) mode. Comparing with commercialized ZIC. HILIC in glycopeptides enrichment of fetuin digest which mixed with 5 mole ratio of albumin bovine (BSA), the as. prepared materials showed higher selectivity in both aspects of the identified number of glycopeptides and anti. interference property. The SPE results demonstrated that the tetrapeptide. based HILIC materials could be a potential tool in large. scale glycosylation analysis. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Analytical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | N-LINKED GLYCOPEPTIDES ; SOLID-PHASE EXTRACTION ; MASS-SPECTROMETRY ; GLYCOSYLATION ; GLYCOPROTEINS ; HETEROGENEITY ; FETUIN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000414612900006 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/149737]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, Wuhan 430070, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li Xiu-Ling,Chen Cheng,Wang Hong-Xi,et al. Novel Tetrapeptide Hydrophilic Interaction Chromatography Materials for High. efficiency Glycopeptide Enrichment[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2017,45(8):1149-1154. |
| APA | Li Xiu-Ling.,Chen Cheng.,Wang Hong-Xi.,Kang Hong-Jian.,Yao Yao.,...&Liang Xin-Miao.(2017).Novel Tetrapeptide Hydrophilic Interaction Chromatography Materials for High. efficiency Glycopeptide Enrichment.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,45(8),1149-1154. |
| MLA | Li Xiu-Ling,et al."Novel Tetrapeptide Hydrophilic Interaction Chromatography Materials for High. efficiency Glycopeptide Enrichment".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 45.8(2017):1149-1154. |
入库方式： OAI收割
来源：大连化学物理研究所
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