N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry
文献类型：期刊论文
| 作者 | Ge, Guangbo1; Cheng, Xina1; Ye, Xueting2; Liu, Dan1; Zhao, Nan1; Gao, Huiyuan2; Wang, Ping1; Zhang, Xiaozhe1 |
| 刊名 | RAPID COMMUNICATIONS IN MASS SPECTROMETRY
 |
| 出版日期 | 2017-11-15 |
| 卷号 | 31期号:21页码:1779-1784 |
| 英文摘要 | Rationale: The matrix plays an essential role in defining detection limits and ionization yields of analytes in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis. Small molecule MALDI-MS analyses commonly suffer from the high background interference generated from matrices. Moreover, the inhomogeneous crystallization of some matrices, such as 2,5-dihydroxybenzoic acid (DHB), is to the detriment of the quality or repeatability of detection. We have found that N-butyl-4-hydroxy-1,8-naphthalimide (BHN) can provide improved performance as a matrix for small molecule analysis. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology |
| 类目[WOS] | Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy |
| 关键词[WOS] | MALDI-TOF MS ; DESORPTION IONIZATION ; PROTEINS ; METABOLITES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000412454500001 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/150076]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China 2.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ge, Guangbo,Cheng, Xina,Ye, Xueting,et al. N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2017,31(21):1779-1784. |
| APA | Ge, Guangbo.,Cheng, Xina.,Ye, Xueting.,Liu, Dan.,Zhao, Nan.,...&Zhang, Xiaozhe.(2017).N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,31(21),1779-1784. |
| MLA | Ge, Guangbo,et al."N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 31.21(2017):1779-1784. |
入库方式： OAI收割
来源：大连化学物理研究所
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