Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane
文献类型：期刊论文
| 作者 | Zhao, Jiuyang2; Yang, Kaiguang3; Liu, Jianhui1,3; Sun, Jingdi2; Zhou, Yuan3; Zhao, Qun3; Li, Senwu1,3; Liu, Lukuan1,3; Zhang, Lihua3; Zhang, Yukui3 |
| 刊名 | SCIENCE BULLETIN
 |
| 出版日期 | 2017-09-30 |
| 卷号 | 62期号:18页码:1251-1255 |
| 关键词 | Proteomic study Complications of hemodialysis Dialysis membrane Ionic liquid |
| 英文摘要 | The complications of hemodialysis accompanied the hemodialysis and threaten the patients' life. Besides the loss of nutrient substance, such as amino acid and vitamin, we found new clues that the adsorbed proteins on common-used polysulfone-based dialysis membrane might be the reason according to the qualitative proteomic study by ionic liquid assisted sample preparation method. Our results indicated that the adsorbed proteins on the membrane were related with complement activation, blood coagulation, and leukocyte-related biological process. The quantitative proteome further demonstrated some significant changes of signal proteins in the post-dialysis plasma after the hemodialysis, such as beta-2-microglobulin and platelet factor-4, which would further verify these new clues. (C) 2017 Science China Press. Published by Elsevier B.V. and Science China Press. All rights reserved. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | POLYETHERSULFONE MEMBRANES ; PROTEIN ADSORPTION ; POLYSULFONE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000412131000008 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/150217]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jiuyang,Yang, Kaiguang,Liu, Jianhui,et al. Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane[J]. SCIENCE BULLETIN,2017,62(18):1251-1255. |
| APA | Zhao, Jiuyang.,Yang, Kaiguang.,Liu, Jianhui.,Sun, Jingdi.,Zhou, Yuan.,...&Zhang, Yukui.(2017).Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane.SCIENCE BULLETIN,62(18),1251-1255. |
| MLA | Zhao, Jiuyang,et al."Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane".SCIENCE BULLETIN 62.18(2017):1251-1255. |
入库方式： OAI收割
来源：大连化学物理研究所
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