Fluorescent Probes for Mitochondria! Reactive Oxygen Species in Biological Systems
文献类型：期刊论文
| 作者 | Han Ke-Li; Lou Zhang-Rong; Li Peng |
| 刊名 | ACTA PHYSICO-CHIMICA SINICA
 |
| 出版日期 | 2017-06-14 |
| 卷号 | 33期号:8页码:1573-1588 |
| 关键词 | Fluorescent probe Mitochondria Reactive oxygen species Small molecule Living cells |
| 英文摘要 | In addition to being the energy powerhouse of the cell, mitochondria are an important source of reactive oxygen species (ROS) during the process of molecular oxygen metabolism. Mitochondrial ROS are closely associated with normal physiological functions as well as human diseases, and participate in cell signaling, nucleic acid and protein damage, and oxidative stress induction. However, the complicated interplay between mitochondrial ROS and the cellular pathological state has not been fully elucidated. It is expected that research on the mitochondrial ROS undertaking in the molecular pathogenesis of human diseases would benefit from development of efficient tools for the detection of these ROS. In recent years, an increasing number of fluorescent probes for mitochondrial ROS with high sensitivity and selectivity have been developed. Here, we present a review of the recent advances in small molecular fluorescent probes for selective detection of ROS inside the mitochondria. In this review, the design, synthesis, characteristics, and applications of the published fluorescent probes for mitochondrial ROS are discussed in detail. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Physical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | PHOTOINDUCED ELECTRON-TRANSFER ; IMAGING HYDROGEN-PEROXIDE ; LIVING CELLS ; NITRIC-OXIDE ; IN-VIVO ; OXIDATIVE STRESS ; TARGETING MITOCHONDRIA ; SELECTIVE DETECTION ; HYPOCHLOROUS ACID ; LIVE CELLS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000405216100012 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/151910]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Liaoning, Peoples R China |
| 推荐引用方式 GB/T 7714 | Han Ke-Li,Lou Zhang-Rong,Li Peng. Fluorescent Probes for Mitochondria! Reactive Oxygen Species in Biological Systems[J]. ACTA PHYSICO-CHIMICA SINICA,2017,33(8):1573-1588. |
| APA | Han Ke-Li,Lou Zhang-Rong,&Li Peng.(2017).Fluorescent Probes for Mitochondria! Reactive Oxygen Species in Biological Systems.ACTA PHYSICO-CHIMICA SINICA,33(8),1573-1588. |
| MLA | Han Ke-Li,et al."Fluorescent Probes for Mitochondria! Reactive Oxygen Species in Biological Systems".ACTA PHYSICO-CHIMICA SINICA 33.8(2017):1573-1588. |
入库方式： OAI收割
来源：大连化学物理研究所
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