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  4. 中科院强磁场科学中心
Using L-STM to directly visualize enzymatic self-assembly/disassembly of nanofibers

文献类型：期刊论文

作者Zheng, Zhen1,2,3; Wang, Jihao1,2,4; Chen, Peiyao1,2,3; Xie, Maolin5; Zhang, Lei1,2; Hou, Yubin1,2; Zhang, Xin1,2; Jiang, Jun4,5; Wang, Junfeng1,2; Lu, Qingyou1,2,3,6
刊名NANOSCALE
出版日期2016
卷号8期号:33页码:15142-15146
DOI10.1039/c6nr03056d
文献子类Article
英文摘要Self-assembly/disassembly is ubiquitous in nature and plays an important role in many biological events. But noninvasive characterization of this process in real time at molecular resolution remains challenging. Herein, using homebuilt liquid-phase scanning tunneling microscopy (L-STM) with ultrahigh stability, we directly visualized enzymatic self-assembly/disassembly of oligopeptide nanofibers in real time for the first time. Static high-resolution L-STM images clearly showed the molecular packing details in the supramolecular nanofiber and the diameter of the nanofiber was consistent with that of cryo transmission electron microscopy (cryo-TEM) observations. Moreover, the self-repairing behavior of the supramolecular nanofibers was also directly observed at high resolution for the first time. This work unprecedentedly revealed new insights into Nature-mimic self-assembly and disassembly at the molecular level. It also illustrates the potential of our homebuilt L-STM in studying delicate biological processes in physiological solution with high resolution.
WOS关键词ATOMIC-FORCE MICROSCOPY ; SCANNING-TUNNELING-MICROSCOPY ; HYDROGELS ; PROTEIN ; DESIGN ; SINGLE
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种英语
WOS记录号WOS:000382068000005
资助机构Collaborative Innovation Center of Suzhou Nano Science and Technology ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; project of Chinese National High Magnetic Field Facilities ; project of Chinese National High Magnetic Field Facilities ; project of Chinese National High Magnetic Field Facilities ; project of Chinese National High Magnetic Field Facilities ; National Natural Science Foundation of China(U1532144 ; National Natural Science Foundation of China(U1532144 ; National Natural Science Foundation of China(U1532144 ; National Natural Science Foundation of China(U1532144 ; 21375121 ; 21375121 ; 21375121 ; 21375121 ; U1532269 ; U1532269 ; U1532269 ; U1532269 ; U1332142 ; U1332142 ; U1332142 ; U1332142 ; U1232210 ; U1232210 ; U1232210 ; U1232210 ; 11204306 ; 11204306 ; 11204306 ; 11204306 ; 11374278) ; 11374278) ; 11374278) ; 11374278) ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; Collaborative Innovation Center of Suzhou Nano Science and Technology ; project of Chinese National High Magnetic Field Facilities ; project of Chinese National High Magnetic Field Facilities ; project of Chinese National High Magnetic Field Facilities ; project of Chinese National High Magnetic Field Facilities ; National Natural Science Foundation of China(U1532144 ; National Natural Science Foundation of China(U1532144 ; National Natural Science Foundation of China(U1532144 ; National Natural Science Foundation of China(U1532144 ; 21375121 ; 21375121 ; 21375121 ; 21375121 ; U1532269 ; U1532269 ; U1532269 ; U1532269 ; U1332142 ; U1332142 ; U1332142 ; U1332142 ; U1232210 ; U1232210 ; U1232210 ; U1232210 ; 11204306 ; 11204306 ; 11204306 ; 11204306 ; 11374278) ; 11374278) ; 11374278) ; 11374278)
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/24019]  
专题合肥物质科学研究院_中科院强磁场科学中心
作者单位1.Chinese Acad Sci, Hefei Sci Ctr, High Magnet Field Lab, Hefei, Anhui, Peoples R China
2.Univ Sci & Technol China, Hefei, Anhui, Peoples R China
3.Univ Sci & Technol China, Dept Chem, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China
4.Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China
5.Univ Sci & Technol China, Dept Chem Phys, Hefei 230026, Anhui, Peoples R China
6.Nanjing Univ, Collaborat Innovat Ctr Adv Microstruct, Nanjing 210093, Jiangsu, Peoples R China
推荐引用方式
GB/T 7714		 Zheng, Zhen,Wang, Jihao,Chen, Peiyao,et al. Using L-STM to directly visualize enzymatic self-assembly/disassembly of nanofibers[J]. NANOSCALE,2016,8(33):15142-15146.
APA Zheng, Zhen.,Wang, Jihao.,Chen, Peiyao.,Xie, Maolin.,Zhang, Lei.,...&Liang, Gaolin.(2016).Using L-STM to directly visualize enzymatic self-assembly/disassembly of nanofibers.NANOSCALE,8(33),15142-15146.
MLA Zheng, Zhen,et al."Using L-STM to directly visualize enzymatic self-assembly/disassembly of nanofibers".NANOSCALE 8.33(2016):15142-15146.

入库方式： OAI收割

来源：合肥物质科学研究院

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