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Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite

文献类型：期刊论文

作者Zhang, Yajiao1,2; Guan, Lingmei4; Yu, Huan1,2; Yan, Yehan1,2; Du, Libo4; Liu, Yang4; Sun, Mingtai1,2; Huang, Dejian3; Wang, Suhua1,2
刊名ANALYTICAL CHEMISTRY
出版日期2016-04-19
卷号88期号:8页码:4426-4431
DOI10.1021/acs.analchem.6b00061
文献子类Article
英文摘要In this paper, we report a benzothiazole-functionalized cyanine fluorescence probe and demonstrate that it is selectively reactive to bisulfite, an intermediate indicator for oxidative stress. The selective reaction can be monitored by distinct ratiometric fluorescence variation favorable for cell imaging and visualization. The original probe can be regenerated in high yield through the elimination of bisulfite from the product by peroxides such as hydrogen peroxide, accompanied by fluorescence turning on at 590 nm, showing a potential application for the detection of peroxides. We successfully applied this probe for fluorescence imaging of bisulfite in cancer cells (MCF-7) treated with bisulfite and hydrogen peroxide as well as a selective detection limit of 0.34 mu M bisulfite in aqueous solution.
WOS关键词INJECTION SPECTROPHOTOMETRIC DETERMINATION ; SULFUR-DIOXIDE DERIVATIVES ; LIVING CELLS ; AQUEOUS-SOLUTION ; SO2 DERIVATIVES ; RAPID DETECTION ; SULFITE ; WATER ; CYSTEINE ; SENSOR
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000374706000036
资助机构National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China(21302187 ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; National Natural Science Foundation of China for Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund(21228702) ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21475134 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 21507135 ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101) ; 91439101)
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/30895]  
专题合肥物质科学研究院_中科院合肥智能机械研究所
作者单位1.Chinese Acad Sci, Inst Intelligent Machines, Hefei 230031, Anhui, Peoples R China
2.Univ Sci & Technol China, Dept Mat Sci & Engn, Hefei 230026, Anhui, Peoples R China
3.Natl Univ Singapore, Dept Chem, Food Sci & Technol Programme, 3 Sci Dr 3, Singapore 117543, Singapore
4.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Yajiao,Guan, Lingmei,Yu, Huan,et al. Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite[J]. ANALYTICAL CHEMISTRY,2016,88(8):4426-4431.
APA Zhang, Yajiao.,Guan, Lingmei.,Yu, Huan.,Yan, Yehan.,Du, Libo.,...&Wang, Suhua.(2016).Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite.ANALYTICAL CHEMISTRY,88(8),4426-4431.
MLA Zhang, Yajiao,et al."Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite".ANALYTICAL CHEMISTRY 88.8(2016):4426-4431.

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来源：合肥物质科学研究院

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