中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
High sensitivity field asymmetric ion mobility spectrometer

文献类型:期刊论文

作者Chavarria, Mario A.1; Matheoud, Alessandro V.1; Marmillod, Philippe1; Liu, Youjiang2; Kong, Deyi2; Brugger, Jurgen1; Boero, Giovanni1
刊名REVIEW OF SCIENTIFIC INSTRUMENTS
出版日期2017-03-01
卷号88期号:3页码:1-14
DOI10.1063/1.4978960
文献子类Article
英文摘要A high sensitivity field asymmetric ion mobility spectrometer (FAIMS) was designed, fabricated, and tested. The main components of the system are a 10.6 eV UV photoionization source, an ion filter driven by a high voltage/high frequency n-MOS inverter circuit, and a low noise ion detector. The ion filter electronics are capable to generate square waveforms with peak-to-peak voltages up to 1000 V at frequencies up to 1 MHz with adjustable duty cycles. The ion detector current amplifier has a gain up to 10(12) V/A with an effective equivalent input noise level down to about 1 fA/Hz(1/2) during operation with the ion filter at the maximum voltage and frequency. The FAIMS system was characterized by detecting different standard chemical compounds. Additionally, we investigated the use of a synchronous modulation/demodulation technique to improve the signal-to-noise ratio in FAIMS measurements. In particular, we implemented the modulation of the compensation voltage with the synchronous demodulation of the ion current. The analysis of the measurements at low concentration levels led to an extrapolated limit of detection for acetone of 10 ppt with an averaging time of 1 s. Published by AIP Publishing.
WOS关键词WAVE-FORM ; MASS-SPECTROMETRY ; ATMOSPHERIC-PRESSURE ; FAIMS ; SEPARATION ; PROTEINS ; DMS
WOS研究方向Instruments & Instrumentation ; Physics
语种英语
WOS记录号WOS:000397871400074
资助机构Ecole Polytechnique Federale de Lausanne (EPFL) ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Ecole Polytechnique Federale de Lausanne (EPFL) ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Sino-Swiss Science and Technology Cooperation (SSSTC) program ; Sino-Swiss Science and Technology Cooperation (SSSTC) program
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/32887]  
专题合肥物质科学研究院_中科院合肥智能机械研究所
作者单位1.Ecole Polytech Fed Lausanne, CH-1015 Lausanne, Switzerland
2.Chinese Acad Sci, Hefei Inst Intelligent Machines, State Key Lab Transducer Technol, Hefei 230031, Peoples R China
推荐引用方式
GB/T 7714
Chavarria, Mario A.,Matheoud, Alessandro V.,Marmillod, Philippe,et al. High sensitivity field asymmetric ion mobility spectrometer[J]. REVIEW OF SCIENTIFIC INSTRUMENTS,2017,88(3):1-14.
APA Chavarria, Mario A..,Matheoud, Alessandro V..,Marmillod, Philippe.,Liu, Youjiang.,Kong, Deyi.,...&Boero, Giovanni.(2017).High sensitivity field asymmetric ion mobility spectrometer.REVIEW OF SCIENTIFIC INSTRUMENTS,88(3),1-14.
MLA Chavarria, Mario A.,et al."High sensitivity field asymmetric ion mobility spectrometer".REVIEW OF SCIENTIFIC INSTRUMENTS 88.3(2017):1-14.

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来源:合肥物质科学研究院

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