EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS
文献类型：期刊论文
| 作者 | YOU, ZB; DU, JZ |
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 1991-03-01 |
| 卷号 | 12期号:2页码:164-166 |
| 关键词 | Argipressin Peptides Corticotropin Releasing Hormone Corticosterone Median Eminence |
| 英文摘要 | The paper mainly stresses on the effect of argipressin (Arg), 2-destyrosyl-3-desphenyl-alanyl-9-desglycyl-9-desglycyl-amide-Arg (Arg4-8), [1-deaminopenicillamine, 2-(o-methyl)tyrosine]-Arg (DPArg) and Arg antiserum on corticotropin releasing hormone (CRH) contents in median eminence (ME) and the level of plasma corticosterone after injected into the third ventricle of rats. The results show: 1) the CRH contents in ME significantly reduced with icv 100, 200, and 800 ng of Arg; 2) 100 ng of Arg4-8 and Arg antiserum (2-mu-l, 1:1 diluted with 0.9% saline) increased CRH contents in ME and enhanced plasma corticosterone; 3) DPArg had no effect on CRH level but blocked the inhibitory role of Arg on central CRH. These results suggest that Arg acts as an inhibitory factor in regulating central CRH level and V1 receptor is involved. |
| 语种 | 英语 |
| WOS记录号 | WOS:A1991FB87500015 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/13267]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | YOU, ZB,DU, JZ. EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS[J]. ACTA PHARMACOLOGICA SINICA,1991,12(2):164-166. |
| APA | YOU, ZB,&DU, JZ.(1991).EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS.ACTA PHARMACOLOGICA SINICA,12(2),164-166. |
| MLA | YOU, ZB,et al."EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS".ACTA PHARMACOLOGICA SINICA 12.2(1991):164-166. |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。