中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework

文献类型:期刊论文

作者Zhang, Ying2; Zhang, Wentao2; Chen, Kai2; Yang, Qingfeng2; Hu, Na1; Suo, Yourui1; Wang, Jianlong2
刊名SENSORS AND ACTUATORS B-CHEMICAL
出版日期2018-06-01
卷号262页码:95-101
关键词Fe3o4/mil-88 Composite Methylene Blue Dye Enhanced Fenton-like Catalysis Glutathione Detection Colorimetric Biosensor
DOI10.1016/j.snb.2018.01.221
英文摘要Glutathione (GSH) as a biothiol is an essential endogenous antioxidant related to various diseases. Since all the biothiols possess similar structures and reaction activities, it is still challenging to detect GSH over cysteine (Cys) and homocysteine (Hcy). In this contribution, we propose a novel approach to sensitively and selectively detect GSH based on Fe3O4/MIL-88-H2O2-methylene blue (MB) heterogeneous system via enhanced Fenton-like reaction. The magnetic metal organic framework (Fe3O4/MIL-88) exhibits synergistic effect on Fenton-like reaction by combining Fe3O4 with MIL-88. In this system, GSH can facilitate the degradation of MB in the presence of Fe3O4/MIL-88 and H2O2, so a detection method for GSH is established via a turn-off colorimetric process. Under the optimal conditions, this approach presents a good linear response to GSH concentration in the ranges of 0-0.55 mu M and 0.55-3 mu M, with a detection limit of 36.9 nM (3 delta/S). Furthermore, the excellent sensitive and selective responses to GSH in serum sample make this assay a promising tool for biological applications due to its simplicity, high efficiency and low cost. (C) 2018 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000427460600013
源URL[http://ir.nwipb.ac.cn/handle/363003/13355]  
专题西北高原生物研究所_中国科学院西北高原生物研究所
作者单位1.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China
2.Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Ying,Zhang, Wentao,Chen, Kai,et al. Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,262:95-101.
APA Zhang, Ying.,Zhang, Wentao.,Chen, Kai.,Yang, Qingfeng.,Hu, Na.,...&Wang, Jianlong.(2018).Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework.SENSORS AND ACTUATORS B-CHEMICAL,262,95-101.
MLA Zhang, Ying,et al."Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework".SENSORS AND ACTUATORS B-CHEMICAL 262(2018):95-101.

入库方式: OAI收割

来源:西北高原生物研究所

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