中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection

文献类型:期刊论文

作者Wu, Lidong2; Lu, Xianbo1; Fu, Xiaochen2; Wu, Lingxia1; Liu, Huan2
刊名SCIENTIFIC REPORTS
出版日期2017-07-12
卷号7
DOI10.1038/s41598-017-05352-7
英文摘要Gold nanoparticles (AuNP) dotted reduction graphene oxide (RGO-AuNP) is used as a platform for an aptamer biosensor to selectively detect 3,3'4,4'-polychlorinated biphenyls (PCB77). By anchoring aptamers onto the binding sites of RGO-AuNP and making use of the synergy effect of RGO and AuNP, the RGO-AuNP based biosensor exhibits superior analytical performances to AuNP based biosensor in terms of sensitivity and repeatability. The sensitivity of RGO-AuNP based aptamers (RGO-AuNP-Ap) biosensor (226.8 mu A cm(-2)) is nearly two times higher than that of Au based biosensors (AuNP-Ap/Au electrode, 147.2 mu A cm(-2)). The RGO-AuNP-Ap/Au biosensor demonstrated a linear response for PCB77 concentrations between 1 pg L-1 and 10 mu g L-1, with a low limit of detection (LOD) of 0.1 pg L-1. The superb LOD satisfies the exposure thresholds (uncontaminated water < 0.1 ng L-1) set out by International Agency for Research on Cancer (IARC) and the Environmental Protection Agency (EPA). The proposed biosensor can be a powerful tool for rapid, sensitive and selective detection of PCBs on site.
语种英语
WOS记录号WOS:000405423000009
源URL[http://cas-ir.dicp.ac.cn/handle/321008/152071]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Chinese Acad Fishery Sci, Key Lab Control Qual & Safety Aquat Prod, Minisrty Agr, Beijing 100141, Peoples R China
推荐引用方式
GB/T 7714
Wu, Lidong,Lu, Xianbo,Fu, Xiaochen,et al. Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection[J]. SCIENTIFIC REPORTS,2017,7.
APA Wu, Lidong,Lu, Xianbo,Fu, Xiaochen,Wu, Lingxia,&Liu, Huan.(2017).Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection.SCIENTIFIC REPORTS,7.
MLA Wu, Lidong,et al."Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection".SCIENTIFIC REPORTS 7(2017).

入库方式: OAI收割

来源:大连化学物理研究所

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