Protein digestomic analysis reveals the bioactivity of deer antler velvet in simulated gastrointestinal digestion
文献类型：期刊论文
| 作者 | Yu, Yang1,2; Jin, Yan2; Wang, Fangjun2; Yan, Jiaze2; Qi, Yanxia1; Ye, Mingliang2 |
| 刊名 | FOOD RESEARCH INTERNATIONAL
 |
| 出版日期 | 2017-06-01 |
| 卷号 | 96页码:182-190 |
| 关键词 | Antler Velvet Protein Digestomics In-vitro Digestion Peptides Lc-ms/ms Bioactivity |
| DOI | 10.1016/j.foodres.2017.04.002 |
| 英文摘要 | Proteins are the most prominent bioactive component in deer antler velvet. The aim of the present study was to track the fate of protein of antler velvet by protein digestomics. The peptide profile identified by LC-MS/MS and the in vitro bioactivity of antler velvet aqueous extract (AAE) were investigated in simulated gastrointestinal digestion. A total of 23, 387 and 417 peptides in AAE, gastric and pancreatic digests were identified using LC-MS/MS, respectively. Collagens, the predominant proteins, released 34 peptides in gastric digests and 146 peptides in pancreatic digests. The gastric and pancreatic digests presented dipeptidyl peptidase IV (DPP-IV) and prolyl endopeptidase (PEP) inhibition activities. Four peptides from digests were proved to be DPP-IV and PEP inhibitory peptides. The results showed that the peptides released from antler velvet protein contributed to the bioactivity of antler velvet during digestion. |
| 语种 | 英语 |
| WOS记录号 | WOS:000402348300019 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/152276]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Dalian Ocean Univ, 52 Heishijiao St, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Yang,Jin, Yan,Wang, Fangjun,et al. Protein digestomic analysis reveals the bioactivity of deer antler velvet in simulated gastrointestinal digestion[J]. FOOD RESEARCH INTERNATIONAL,2017,96:182-190. |
| APA | Yu, Yang,Jin, Yan,Wang, Fangjun,Yan, Jiaze,Qi, Yanxia,&Ye, Mingliang.(2017).Protein digestomic analysis reveals the bioactivity of deer antler velvet in simulated gastrointestinal digestion.FOOD RESEARCH INTERNATIONAL,96,182-190. |
| MLA | Yu, Yang,et al."Protein digestomic analysis reveals the bioactivity of deer antler velvet in simulated gastrointestinal digestion".FOOD RESEARCH INTERNATIONAL 96(2017):182-190. |
入库方式： OAI收割
来源：大连化学物理研究所
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