Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis
文献类型：期刊论文
| 作者 | Li, Xin1 ; Jiang, Hao2; Luo, Zhaofeng2; Chang, Young-Tae3; Zhang, Liyun1
|
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2016 |
| 卷号 | 52期号:58页码:9086-9088 |
| DOI | 10.1039/c6cc00439c |
| 文献子类 | Article |
| 英文摘要 | A fluorescent sensor - InR - with disaggregation-induced emission (DIE) characteristics has been developed for the label free detection of RecA inteins from Mycobacterium tuberculosis. Mechanistic studies demonstrate that InR binds at a hydrophobic pocket of RecA inteins, which is constituted by Gly435, Glu434, Arg405 and Arg 7, resulting in the disaggregation and recovery of its fluorescence. |
| WOS关键词 | AMINO-ACID ; PROTEINS ; PURIFICATION |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000379431000026 |
| 资助机构 | national "973'' program(2014CB932002) ; national "973'' program(2014CB932002) ; national "973'' program(2014CB932002) ; national "973'' program(2014CB932002) ; Natural Science Foundation of China(11105150) ; Natural Science Foundation of China(11105150) ; Natural Science Foundation of China(11105150) ; Natural Science Foundation of China(11105150) ; national "973'' program(2014CB932002) ; national "973'' program(2014CB932002) ; national "973'' program(2014CB932002) ; national "973'' program(2014CB932002) ; Natural Science Foundation of China(11105150) ; Natural Science Foundation of China(11105150) ; Natural Science Foundation of China(11105150) ; Natural Science Foundation of China(11105150) |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/22482]  |
| 专题 | 合肥物质科学研究院_技术生物与农业工程研究所 |
| 作者单位 | 1.Chinese Acad Sci, Inst Tech Biol & Agr Engn, Key Lab Ion Beam Bioengn, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China 2.Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Core Facil Ctr Life Sci, Sch Life Sci, Hefei 230026, Peoples R China 3.Natl Univ Singapore, Dept Chem, 3 Sci Dr 2, Singapore 117543, Singapore |
| 推荐引用方式 GB/T 7714 | Li, Xin,Jiang, Hao,Luo, Zhaofeng,et al. Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis[J]. CHEMICAL COMMUNICATIONS,2016,52(58):9086-9088. |
| APA | Li, Xin,Jiang, Hao,Luo, Zhaofeng,Chang, Young-Tae,&Zhang, Liyun.(2016).Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis.CHEMICAL COMMUNICATIONS,52(58),9086-9088. |
| MLA | Li, Xin,et al."Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis".CHEMICAL COMMUNICATIONS 52.58(2016):9086-9088. |
入库方式： OAI收割
来源：合肥物质科学研究院
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