中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 合肥物质科学研究院
  3. 中国科学院合肥物质科学研究院
  4. 技术生物与农业工程研究所
Multi-Walled Carbon Nanotubes Induced the Developmental Abnormality of Caenorhabditis elegans

文献类型：期刊论文

作者Luo, Xun1,2,4; Xu, Shengmin1,3; Yang, Yaning1,3; Zhang, Yajun1,3; Wu, Lijun1,2,3
刊名JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
出版日期2017-06-01
卷号17期号:6页码:3913-3919
关键词Mwcnts Mwcnts-oh C. Elegans Developmental Abnormality
DOI10.1166/jnn.2017.13747
文献子类Article
英文摘要Multi-walled carbon nanotubes (MWCNTs) are one of the most popular nanoscale carbon products nowadays. However, the toxicity of MWCNTs remains largely unclear. In the present study, we used a well-established in vivo model organism, Caenorhabditis elegans (C. elegans), to examine the effects of MWCNTs on its development time, brood size and life span. We found that exposure of C. elegans to MWCNTs or hydroxyl multi-wall carbon nanotubes (MWCNTs-OH) caused a dose-dependent decrease both in brood size and life span. Compared with MWCNTs group, the MWCNTs-OH exposed group showed less toxic, especially for the development time. Our finding coincided with the ROS generation in worms, and suggested that differences of MWCNTs and MWCNTs-OH in toxicity to C. elegans might be caused by induced ROS.
WOS关键词ENVIRONMENTAL RELEVANT CONCENTRATIONS ; LIFE-SPAN ; BODY-SIZE ; C-ELEGANS ; TOXICITY ; NANOPARTICLES ; MECHANISM ; GENETICS
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种英语
WOS记录号WOS:000402483900039
资助机构National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; National Basic Research 973 Program(2014CB932002) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14030502) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182) ; National Natural Science Foundation of China(81301182)
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/31898]  
专题合肥物质科学研究院_技术生物与农业工程研究所
作者单位1.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab Ion Beam Bioengn, Hefei 230031, Anhui, Peoples R China
2.Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Anhui, Peoples R China
3.Key Lab Environm Toxicol & Pollut Control Technol, Hefei 230031, Anhui, Peoples R China
4.Huainan Normal Univ, Sch Bioengn, Huainan 232038, Peoples R China
推荐引用方式
GB/T 7714		 Luo, Xun,Xu, Shengmin,Yang, Yaning,et al. Multi-Walled Carbon Nanotubes Induced the Developmental Abnormality of Caenorhabditis elegans[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2017,17(6):3913-3919.
APA Luo, Xun,Xu, Shengmin,Yang, Yaning,Zhang, Yajun,&Wu, Lijun.(2017).Multi-Walled Carbon Nanotubes Induced the Developmental Abnormality of Caenorhabditis elegans.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,17(6),3913-3919.
MLA Luo, Xun,et al."Multi-Walled Carbon Nanotubes Induced the Developmental Abnormality of Caenorhabditis elegans".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 17.6(2017):3913-3919.

入库方式： OAI收割

来源：合肥物质科学研究院

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。