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  2. 合肥物质科学研究院
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  4. 中科院强磁场科学中心
c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice

文献类型：期刊论文

作者Wu, Rong1,2; Sun, Jian-guang1,3; Wang, Ji-qiu4; Li, Binhua5; Liu, Qingsong5; Ning, Guang4; Jin, Wanzhu6; Yuan, Zengqiang1,2,7
刊名DIABETOLOGIA
出版日期2017-05-01
卷号60期号:5页码:900-910
DOI10.1007/s00125-016-4202-2
文献子类Article
英文摘要High-energy diets are among the main causes of the global epidemic of metabolic disorders, including obesity and type 2 diabetes. The mechanisms of high-energy-diet-induced metabolic disorders are complex and largely unknown. The non-receptor tyrosine kinase c-Abl plays an important role in adipogenesis in vitro but its role in vivo in the regulation of metabolism is still elusive. Hence, we sought to address the role of c-Abl in diet-induced obesity and obesity-associated insulin resistance.
WOS关键词CHRONIC MYELOID-LEUKEMIA ; CHRONIC MYELOGENOUS LEUKEMIA ; HUMAN ADIPOSE-TISSUE ; TYROSINE KINASE ; ADIPOCYTE DIFFERENTIATION ; ADIPONECTIN LEVELS ; IMATINIB MESYLATE ; CELLS ROLE ; RESISTANCE ; STRESS
WOS研究方向Endocrinology & Metabolism
语种英语
WOS记录号WOS:000398997400018
资助机构National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; 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National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; 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源URL[http://ir.hfcas.ac.cn:8080/handle/334002/33401]  
专题合肥物质科学研究院_中科院强磁场科学中心
作者单位1.Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, 15 Datun Rd, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China
3.Univ Chinese Acad Sci, Sino Danish Ctr Neurosci Program, Beijing, Peoples R China
4.Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Shanghai, Peoples R China
5.Chinese Acad Sci, High Field Magnet Lab, Hefei, Anhui, Peoples R China
6.Chinese Acad Sci, Inst Zool, Key Lab Anim Ecol & Conservat Biol, 1 Beichen West Rd, Beijing 100101, Peoples R China
7.Beijing Inst Brain Disorders, Ctr Alzheimers Dis, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Wu, Rong,Sun, Jian-guang,Wang, Ji-qiu,et al. c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice[J]. DIABETOLOGIA,2017,60(5):900-910.
APA Wu, Rong.,Sun, Jian-guang.,Wang, Ji-qiu.,Li, Binhua.,Liu, Qingsong.,...&Yuan, Zengqiang.(2017).c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice.DIABETOLOGIA,60(5),900-910.
MLA Wu, Rong,et al."c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice".DIABETOLOGIA 60.5(2017):900-910.

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来源：合肥物质科学研究院

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