Polyanionic Antimicrobial Membranes: An Experimental and Theoretical Study
文献类型：期刊论文
| 作者 | Guo, Jiangna1; Xu, Qiming2; Shi, Rongwei3; Zheng, Zhiqiang1; Mao, Hailei2; Yan, Feng1 |
| 刊名 | LANGMUIR
 |
| 出版日期 | 2017-05-02 |
| 卷号 | 33期号:17页码:4346-4355 |
| DOI | 10.1021/acs.langmuir.7b00185 |
| 文献子类 | Article |
| 英文摘要 | Polycationic polymers have been widely used as antimicrobial materials because of their broad spectrum activity and potential use as new antibiotics. Herein, we report the synthesis of polyanionic antimicrobial membranes by in situ photo-cross-linking of a sulfate based anionic monomer, followed by cation-exchange with organic (quaternary ammonium or imidazolium) or metal (Ag+, Cu2+, Fe3+, Zn2+, Na+, K+) cations. The resultant polyanionic membranes show high and broad spectrum antibacterial activities against both bacteria (Escherichia coli, Staphylococcus aureus) and fungi (Candida albicans ). In addition, the polyanionic antimicrobial membranes efficiently inhibited the formation of biofilms by SC5314 and its crk1 gene deleted (Delta crk1) C. albicans strains. Furthermore, the synthesized polyanionic membranes exhibit good blood compatibility, low cytotoxicity and long-term antibacterial stability, demonstrating safe antimicrobial materials in the application of healthcare. |
| WOS关键词 | POLY(IONIC LIQUID) MEMBRANES ; SURFACE-CHARGE CONTROL ; METAL-ION BINDING ; ANTIBACTERIAL ACTIVITY ; BIOLOGICAL APPLICATIONS ; IN-SITU ; NANOPARTICLES ; BACTERIA ; ANTIBIOFILM ; COATINGS |
| WOS研究方向 | Chemistry ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000400723500028 |
| 资助机构 | National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; National Science Foundation for Distinguished Young Scholars(21425417) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Natural Science Foundation of China(21274101) ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions ; Priority Academic Program Development of Jiangsu Higher Education Institutions |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/33413]  |
| 专题 | 合肥物质科学研究院_技术生物与农业工程研究所 |
| 作者单位 | 1.Soochow Univ, Dept Polymer Sci & Engn, Coll Chem Chem Engn & Mat Sci, Jiangsu Key Lab Adv Funct Polymer Design & Applic, Suzhou 215123, Peoples R China 2.Fudan Univ, Zhongshan Hosp, Dept Anesthesiol & Crit Care Med, 180 Fenglin Rd, Shanghai 200032, Peoples R China 3.Chinese Acad Sci, Inst Tech Biol & Agr Engn, Hefei Inst Phys Sci, 350 Shushanhu Rd, Hefei 230031, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Jiangna,Xu, Qiming,Shi, Rongwei,et al. Polyanionic Antimicrobial Membranes: An Experimental and Theoretical Study[J]. LANGMUIR,2017,33(17):4346-4355. |
| APA | Guo, Jiangna,Xu, Qiming,Shi, Rongwei,Zheng, Zhiqiang,Mao, Hailei,&Yan, Feng.(2017).Polyanionic Antimicrobial Membranes: An Experimental and Theoretical Study.LANGMUIR,33(17),4346-4355. |
| MLA | Guo, Jiangna,et al."Polyanionic Antimicrobial Membranes: An Experimental and Theoretical Study".LANGMUIR 33.17(2017):4346-4355. |
入库方式： OAI收割
来源：合肥物质科学研究院
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