Norisoprenoids from the Brown Alga Sargassum naozhouense Tseng et Lu
文献类型：期刊论文
| 作者 | Peng, Y; Huang, RM; Lin, XP; Liu, YH; py00_2006@126.com; huangriming@scau.edu.cn; xiupinglin@hotmail.com; yonghongliu@scsio.ac.cn |
| 刊名 | MOLECULES
 |
| 出版日期 | 2018 |
| 卷号 | 23期号:2页码:-348 |
| 英文摘要 | A new C-11-norisoprenoid derivative, sargassumone (1), has been isolated from Sargassum naozhouense together with six known norisoprenoids and a highly oxygenated cyclopentene: (2R, 6S, 8S, 9S)-hexahydro-2,9-dihydroxy-4,4,8-trimethyl-6-acetyloxy-3(2H)-benzofuranone (2), (6S, 8S, 9R)-hexahydro-6,9-dihydroxy-4,4,8-trimethyl-2(2H)-benzofuranone (3), (6S, 8S, 9R)-hexahydro6,9- dihydroxy-4,4,8-trimethyl-2(2H)-benzofuranone (4), loliolide (5), (+)-epiloliolide (6), spheciospongones A (7), and (+)-kjellmanianone (8). compound 1 was identified on the basis of nuclear magnetic resonance (NMR) and mass spectrometry (MS) analysis, and the absolute stereochemistry was defined by NOESY spectroscopy, minimizing energy calculation, and circular dichroism (CD) spectra. The known compounds 2-8, isolated from S. naozhouense for the first time, were identified by comparison of their physical and spectroscopic data with those reported in the literature. compound 6 was tested for its inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), antioxidant activity with 1,1-diphyl-2-picrylhydrazyl (DPPH) free radicals, and antimicrobial activity against resistant clinical isolates of Candida albicans, methicillin-resistant Staphylococcus aureus (MRSA), and Escherichia coli. |
| 学科主题 | Biochemistry & Molecular Biology ; Chemistry |
| WOS关键词 | brown alga ; Sargassum naozhouense ; norisoprenoids ; cyclopentene |
| 资助项目 | LMB |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17004]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | py00_2006@126.com; huangriming@scau.edu.cn; xiupinglin@hotmail.com; yonghongliu@scsio.ac.cn |
| 推荐引用方式 GB/T 7714 | Peng, Y,Huang, RM,Lin, XP,et al. Norisoprenoids from the Brown Alga Sargassum naozhouense Tseng et Lu[J]. MOLECULES,2018,23(2):-348. |
| APA | Peng, Y.,Huang, RM.,Lin, XP.,Liu, YH.,py00_2006@126.com.,...&yonghongliu@scsio.ac.cn.(2018).Norisoprenoids from the Brown Alga Sargassum naozhouense Tseng et Lu.MOLECULES,23(2),-348. |
| MLA | Peng, Y,et al."Norisoprenoids from the Brown Alga Sargassum naozhouense Tseng et Lu".MOLECULES 23.2(2018):-348. |
入库方式： OAI收割
来源：南海海洋研究所
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