Hygrocin C from marine-derived Streptomyces sp SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian
文献类型：期刊论文
| 作者 | Wang, J; Nong, XH; Amin, M; Qi, SH |
| 刊名 | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
 |
| 出版日期 | 2018 |
| 卷号 | 102期号:3页码:1417-1427 |
| 通讯作者 | shuhuaqi@scsio.ac.cn |
| 英文摘要 | Several ansamycins have been reported to inhibit bacterial biofilm formation and accelerate the eradication of developed biofilms, but little is known about the effect of hygrocin C, an ansamycin, on bacterial biofilm formation. Here, hygrocin C was isolated from the marine-derived Streptomyces sp. SCSGAA 0027 and reported for the first time to be capable of inhibiting the biofilm formation of Staphylococcus aureus and Bacillus amyloliquefaciens SCSGAB0082 with the production of anti-microbial lipopeptides from South China Sea gorgonian Subergorgia suberosa at concentrations of less than minimum inhibitory concentrations. Moreover, hygrocin C also promoted the eradication of developed biofilms, affected the biofilm architecture, and lowered the extracellular polymeric matrix formation, cell motility, and surface hydrophobicity in B. amyloliquefaciens, which was in accordance with the inhibition of biofilm formation. Furthermore, transcriptome analysis revealed that hygrocin C altered the transcripts of several genes associated with bacterial chemotaxis and flagellar, two-component system and the synthesis of arginine and histidine, which are important for bacterial biofilm formation. In conclusion, hygrocin C could be used as a potential biofilm inhibitor against S. aureus and B. amyloliquefaciens. But further genetic investigations are needed to provide more details for elucidation of the molecular mechanisms responsible for the effects of hygrocin C on B. amyloliquefaciens biofilm formation. |
| 学科主题 | Biotechnology & Applied Microbiology |
| 关键词[WOS] | Biofilm ; Hygrocin C ; B. amyloliquefaciens ; Transcriptome analysis |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17013]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang, J,Nong, XH,Amin, M,et al. Hygrocin C from marine-derived Streptomyces sp SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(3):1417-1427. |
| APA | Wang, J,Nong, XH,Amin, M,&Qi, SH.(2018).Hygrocin C from marine-derived Streptomyces sp SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,102(3),1417-1427. |
| MLA | Wang, J,et al."Hygrocin C from marine-derived Streptomyces sp SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 102.3(2018):1417-1427. |
入库方式： OAI收割
来源：南海海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。