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Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae

文献类型：期刊论文

作者Qiao, Ming-Feng1,2; Ji, Nai-Yun1; Liu, Xiang-Hong1; Li, Fang3; Xue, Qin-Zhao1
刊名NATURAL PRODUCT COMMUNICATIONS
出版日期2010-10-01
卷号5期号:10页码:1575-1578
关键词Asporyergosterol Red Alga Heterosiphonia Japonica Endophytic Fungus Aspergillus Oryzae
ISSN号1934-578X
产权排序[Qiao, Ming-Feng; Ji, Nai-Yun; Liu, Xiang-Hong; Xue, Qin-Zhao] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Qiao, Ming-Feng] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China; [Li, Fang] Qingdao Univ Sci & Technol, Qingdao 266042, Peoples R China
通讯作者Ji, NY, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
文献子类Article
英文摘要Asporyergosterol (1), a new steroid with an E double bond between C-17 and C-20, was identified from the culture extracts of Aspergillus oryzae, an endophytic fungus isolated from the marine red alga Heterosiphonia japonica. Moreover, four known steroids including (22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (2), (22E,24R)-3 beta-hydroxyergosta-5,8,22-trien-7-one (3), (22E,24R)-ergosta-7,22-dien-3 beta,5 alpha,6 beta-triol (4), and (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (5) were isolated. Structures of these compounds were unambiguously established by spectroscopic techniques and by comparison with literature values. All the isolates exhibited low activity to modulate acetylcholinesterase (AChE).; Asporyergosterol (1), a new steroid with an E double bond between C-17 and C-20, was identified from the culture extracts of Aspergillus oryzae, an endophytic fungus isolated from the marine red alga Heterosiphonia japonica. Moreover, four known steroids including (22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (2), (22E,24R)-3 beta-hydroxyergosta-5,8,22-trien-7-one (3), (22E,24R)-ergosta-7,22-dien-3 beta,5 alpha,6 beta-triol (4), and (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (5) were isolated. Structures of these compounds were unambiguously established by spectroscopic techniques and by comparison with literature values. All the isolates exhibited low activity to modulate acetylcholinesterase (AChE).
学科主题Chemistry ; Medicinal ; Food Science & Technology
URL标识查看原文
WOS关键词FUNGI
WOS研究方向Pharmacology & Pharmacy ; Food Science & Technology
语种英语
WOS记录号WOS:000283380800012
资助机构Chinese Academy of Sciences for Key Topics in Innovation Engineering [KZCX2-YW-QN209, KSCX2-YW-G-073, KZCX2-YW-225]; Shandong Province Natural Science Foundation [ZR2009BQ021]; Yantai Municipal Sci-Tech Development Program [2009164]; Foundation of the Chinese Academy of Sciences
公开日期2011-07-14
源URL[http://ir.yic.ac.cn/handle/133337/3746]  
专题烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
烟台海岸带研究所_中科院烟台海岸带研究所知识产出
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Qingdao Univ Sci & Technol, Qingdao 266042, Peoples R China
推荐引用方式
GB/T 7714		 Qiao, Ming-Feng,Ji, Nai-Yun,Liu, Xiang-Hong,et al. Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae[J]. NATURAL PRODUCT COMMUNICATIONS,2010,5(10):1575-1578.
APA Qiao, Ming-Feng,Ji, Nai-Yun,Liu, Xiang-Hong,Li, Fang,&Xue, Qin-Zhao.(2010).Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae.NATURAL PRODUCT COMMUNICATIONS,5(10),1575-1578.
MLA Qiao, Ming-Feng,et al."Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae".NATURAL PRODUCT COMMUNICATIONS 5.10(2010):1575-1578.

入库方式： OAI收割

来源：烟台海岸带研究所

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