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A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities

文献类型：期刊论文

作者Zhang, Hongyu1,2; Wang, Hongpeng3; Cui, Hongli1; Li, Zonggang4; Xie, Zeping1; Pu, Yang1; Li, Fuchao5; Qin, Song1
刊名MARINE DRUGS
出版日期2011-09-01
卷号9期号:9页码:1502-1509
关键词Streptomyces Anthracene Structure Establishment Cytotoxicity
ISSN号1660-3397
产权排序[Zhang, Hongyu; Cui, Hongli; Xie, Zeping; Pu, Yang; Qin, Song] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Zhang, Hongyu] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China; [Wang, Hongpeng] Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany; [Li, Zonggang] China Agr Univ, Yantai Inst China Agr Univ, Yantai 264670, Peoples R China; [Li, Fuchao] Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
通讯作者Qin, S (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
文献子类Article
英文摘要A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549.; A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549.
学科主题Pharmacology & Pharmacy
URL标识查看原文
WOS关键词ANTIBIOTICS
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000298927500005
资助机构CAS, Chinese Academy of Sciences[JQ200914, KSCX2-YW-G-073, KZCX2-YW-216, KZCX2-YW-209]; National Natural Science Foundation of China[31000037]
公开日期2012-03-06
源URL[http://ir.yic.ac.cn/handle/133337/5349]  
专题烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany
4.China Agr Univ, Yantai Inst China Agr Univ, Yantai 264670, Peoples R China
5.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Hongyu,Wang, Hongpeng,Cui, Hongli,et al. A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities[J]. MARINE DRUGS,2011,9(9):1502-1509.
APA Zhang, Hongyu.,Wang, Hongpeng.,Cui, Hongli.,Li, Zonggang.,Xie, Zeping.,...&Qin, Song.(2011).A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities.MARINE DRUGS,9(9),1502-1509.
MLA Zhang, Hongyu,et al."A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities".MARINE DRUGS 9.9(2011):1502-1509.

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来源：烟台海岸带研究所

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