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Secondary Metabolites from an Algicolous Aspergillus versicolor Strain

文献类型：期刊论文

作者Miao, Feng-Ping1; Li, Xiao-Dong1; Liu, Xiang-Hong1; Cichewicz, Robert H.2; Ji, Nai-Yun1
刊名MARINE DRUGS
出版日期2012
卷号10期号:1页码:131-139
关键词Sargassum Thunbergii Aspergillus Versicolor Asperversin a 9 Xi-o-2(2 3-dimethylbut-3-enyl)Brevianamide q
ISSN号1660-3397
产权排序[Miao, Feng-Ping; Li, Xiao-Dong; Liu, Xiang-Hong; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Cichewicz, Robert H.] Univ Oklahoma, Dept Chem & Biochem, Nat Prod Discovery Grp, Norman, OK 73019 USA
通讯作者Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. fpmiao@yic.ac.cn ; imnli@163.com ; xianghong1127@163.com ; rhcichewicz@ou.edu ; nyji@yic.ac.cn
文献子类Article
英文摘要Two new compounds, asperversin A (1) and 9 xi-O-2(2,3-dimethylbut-3-enyl)brevianamide Q (2), and nine known compounds, brevianamide K (3), brevianamide M (4), aversin (5), 6,8-di-O-methylnidurufin (6), 6,8-di-O-methylaverufin (7), 6-O-methylaverufin (8), 5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (9), ergosta-7,22-diene-3 beta,5 alpha,6 beta-triol (10), and 6 beta-methoxyergosta-7,22-diene-3 beta,5 alpha-diol (11), were obtained from the culture of Aspergillus versicolor, an endophytic fungus isolated from the marine brown alga Sargassum thunbergii. The structures of these compounds were established by spectroscopic techniques. Compounds 4, 7 and 8 exhibited antibacterial activities against Escherichia coli and Staphyloccocus aureus, and 7 also showed lethality against brine shrimp (Artemia salina) with an LC(50) value of 0.5 mu g/mL.; Two new compounds, asperversin A (1) and 9 xi-O-2(2,3-dimethylbut-3-enyl)brevianamide Q (2), and nine known compounds, brevianamide K (3), brevianamide M (4), aversin (5), 6,8-di-O-methylnidurufin (6), 6,8-di-O-methylaverufin (7), 6-O-methylaverufin (8), 5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (9), ergosta-7,22-diene-3 beta,5 alpha,6 beta-triol (10), and 6 beta-methoxyergosta-7,22-diene-3 beta,5 alpha-diol (11), were obtained from the culture of Aspergillus versicolor, an endophytic fungus isolated from the marine brown alga Sargassum thunbergii. The structures of these compounds were established by spectroscopic techniques. Compounds 4, 7 and 8 exhibited antibacterial activities against Escherichia coli and Staphyloccocus aureus, and 7 also showed lethality against brine shrimp (Artemia salina) with an LC(50) value of 0.5 mu g/mL.
学科主题Pharmacology & Pharmacy
URL标识查看原文
WOS关键词ASSIGNMENTS
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000299541800010
资助机构National Natural Science Foundation of China[41106137, 41106136]; Chinese Academy of Sciences[KZCX2-YW-QN209, KSCX2-EW-G-12B]; Foundation of the Chinese Academy of Sciences
公开日期2012-06-13
源URL[http://ir.yic.ac.cn/handle/133337/5576]  
专题烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Univ Oklahoma, Dept Chem & Biochem, Nat Prod Discovery Grp, Norman, OK 73019 USA
推荐引用方式
GB/T 7714		 Miao, Feng-Ping,Li, Xiao-Dong,Liu, Xiang-Hong,et al. Secondary Metabolites from an Algicolous Aspergillus versicolor Strain[J]. MARINE DRUGS,2012,10(1):131-139.
APA Miao, Feng-Ping,Li, Xiao-Dong,Liu, Xiang-Hong,Cichewicz, Robert H.,&Ji, Nai-Yun.(2012).Secondary Metabolites from an Algicolous Aspergillus versicolor Strain.MARINE DRUGS,10(1),131-139.
MLA Miao, Feng-Ping,et al."Secondary Metabolites from an Algicolous Aspergillus versicolor Strain".MARINE DRUGS 10.1(2012):131-139.

入库方式： OAI收割

来源：烟台海岸带研究所

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