Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma
文献类型:期刊论文
作者 | Zhang, Yong1![]() |
刊名 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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出版日期 | 2015-02-05 |
卷号 | 34 |
关键词 | E-cadherin Dendritic Cell t Cell Lung Cancer Activity |
ISSN号 | 1756-9966 |
DOI | 10.1186/s13046-015-0126-9 |
文献子类 | Article |
英文摘要 | Background: Agonistic CD40 antibodies have been demonstrated to activate antigen-presenting cells (APCs) and enhance antitumour T cell responses, thereby providing a new therapeutic option in cancer immunotherapy. In agonistic CD40 antibody-mediated inflammatory responses, a novel subset of E-cadherin + dendritic cells (DCs) has been identified, and little is known about the role of these DCs in tumour immunity. This study investigated the effect of anti-CD40-mediated inflammatory E-cadherin + DCs in murine Lewis lung carcinoma (LLC). |
WOS关键词 | IN-VIVO ; TUMOR-GROWTH ; LYMPH-NODES ; CANCER ; CD40 ; THERAPY ; MICE ; DIFFERENTIATION ; IMMUNOTHERAPY ; POPULATION |
WOS研究方向 | Oncology |
语种 | 英语 |
WOS记录号 | WOS:000350440200001 |
出版者 | BIOMED CENTRAL LTD |
资助机构 | National Natural Science Foundations of China(81171979, 81372260) ; Doctoral fund(20110142110005) |
源URL | [http://ir.yic.ac.cn/handle/133337/24040] ![]() |
专题 | 烟台海岸带研究所_山东省海岸带环境工程技术研究中心 烟台海岸带研究所_近岸生态与环境实验室 |
通讯作者 | Liu, Li |
作者单位 | 1.Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Ctr Canc, Wuhan 430023, Hubei, Peoples R China 2.Hainan Canc Hosp, Haikou, Hainan, Peoples R China 3.Cent Hosp Wuhan, Dept Oncol, Wuhan, Hunan, Peoples R China 4.Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Cardiol,Lab Cardiovasc Immunol, Wuhan 430023, Hubei, Peoples R China 5.Chinese Acad Sci, Anal & Testing Ctr, Inst Hydro Biol, Wuhan, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Yong,Hu, Xiaoyan,Hu, Yue,et al. Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma[J]. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,2015,34. |
APA | Zhang, Yong.,Hu, Xiaoyan.,Hu, Yue.,Teng, Kai.,Zhang, Kai.,...&Liu, Li.(2015).Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma.JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,34. |
MLA | Zhang, Yong,et al."Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma".JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 34(2015). |
入库方式: OAI收割
来源:烟台海岸带研究所
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