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Uptake pathways and subcellular fractionation of Cd in the polychaete Nereis diversicolor

文献类型：期刊论文

作者Li, Lianzhen1,2; Liu, Xiaoli1,2,3; You, Liping1,2,3; Zhang, Linbao1,2,3; Zhao, Jianmin1,2; Wu, Huifeng1,2
刊名ECOTOXICOLOGY
出版日期2012
卷号21期号:1页码:104-110
关键词Cd Uptake Mechanism Metal Accumulation Nereis Diversicolor
ISSN号0963-9292
产权排序[Li, Lianzhen; Liu, Xiaoli; You, Liping; Zhang, Linbao; Zhao, Jianmin; Wu, Huifeng] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Li, Lianzhen; Liu, Xiaoli; You, Liping; Zhang, Linbao; Zhao, Jianmin; Wu, Huifeng] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Liu, Xiaoli; You, Liping; Zhang, Linbao] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
通讯作者Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
文献子类Article
英文摘要Polychaetes have often been utilized as indicator species to investigate the impacts of pollutants, such as heavy metals. The uptake of Cd by the polychaete Nereis diversicolor was determined at varying Ca concentrations and with pre-exposure to Ca ion channel blockers and metabolic inhibitors in simulated sea water over 1 week period. The supply of Ca in simulated sea water inhibited Cd uptake and increased Ca concentration in N. diversicolor after 10 mu M Cd exposure. Pre-exposure to a Ca-channel blocker (Lanthanum) significantly inhibited Cd uptake, suggesting that the uptake of Cd was exerted at a Ca channel. N-ethylmaleimide, which specifically binds to sulfhydryl groups, inhibited Cd uptake at 10 mu M, implying that the transport of Cd is carrier-mediated by proteins or other SH-containing compounds. Subcellular Cd distribution analysis showed that more than 60% of the total Cd associated with the cytosolic fraction. The presence of higher concentration of Ca in simulated sea water did not impact the proportional subcellular distribution of Cd in N. diversicolor. Nevertheless, the supply of Ca could significantly lower Cd concentration in cytosol and cellular debris. The present study provides evidence that Cd transport by N. diversicolor was mediated mainly through lanthanum- sensitive Ca ion channels and accumulated by SH-containing compounds. These results help to understand the uptake mechanism and subcellular distribution of Cd in polychaetes.
学科主题Environmental Sciences & Ecology ; Toxicology
URL标识查看原文
WOS关键词SCALLOP CHLAMYS-NOBILIS ; CADMIUM UPTAKE ; MEMBRANE-VESICLES ; ZINC TRANSPORT ; PERNA-VIRIDIS ; TRACE-METALS ; CALCIUM ; INHIBITION ; EARTHWORMS ; MECHANISMS
WOS研究方向Environmental Sciences & Ecology ; Toxicology
语种英语
WOS记录号WOS:000298996900012
资助机构Chinese Academy of Sciences[KZCX2-YW-223, KZCX2-YW-225]; SDSFC[ZR2009CZ008]; Key Laboratory of Pollution Processes and Environmental Criteria (Nankai University); Chinese Academy of Sciences, Ministry of Education[KL-PPEC-2010-6]; CAS/SAFEA
公开日期2012-06-13
源URL[http://ir.yic.ac.cn/handle/133337/5622]  
专题烟台海岸带研究所_近岸生态与环境实验室
烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Li, Lianzhen,Liu, Xiaoli,You, Liping,et al. Uptake pathways and subcellular fractionation of Cd in the polychaete Nereis diversicolor[J]. ECOTOXICOLOGY,2012,21(1):104-110.
APA Li, Lianzhen,Liu, Xiaoli,You, Liping,Zhang, Linbao,Zhao, Jianmin,&Wu, Huifeng.(2012).Uptake pathways and subcellular fractionation of Cd in the polychaete Nereis diversicolor.ECOTOXICOLOGY,21(1),104-110.
MLA Li, Lianzhen,et al."Uptake pathways and subcellular fractionation of Cd in the polychaete Nereis diversicolor".ECOTOXICOLOGY 21.1(2012):104-110.

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来源：烟台海岸带研究所

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