Flexible electrochemical biosensors based on graphene nanowalls for the real-time measurement of lactate
文献类型：期刊论文
| 作者 | Chen, Qianwei1,2; Sun, Tai2 ; Song, Xuefen2; Ran, Qincui2; Yu, Chongsheng2; Yang, Jun2; Feng, Hua1; Yu, Leyong2; Wei, Dapeng2
|
| 刊名 | NANOTECHNOLOGY
 |
| 出版日期 | 2017-08-04 |
| 卷号 | 28期号:31页码:8 |
| 关键词 | graphene nanowalls biosensor oxygen-plasma lactate oxidase lactate |
| ISSN号 | 0957-4484 |
| DOI | 10.1088/1361-6528/aa78bc |
| 通讯作者 | Feng, H (reprint author), Third Mil Med Univ, Southwest Hosp, Dept Neurosurg, Chongqing 400038, Peoples R China. ; Sun, T ; Wei, DP (reprint author), Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing Key Lab Multi Scale Mfg Technol, Chongqing 400714, Peoples R China. |
| 英文摘要 | We demonstrate a flexible biosensor for lactate detection based on L-lactate oxidase immobilized by chitosan film cross-linked with glutaraldehyde on the surface of a graphene nanowall (GNW) electrode. The oxygen-plasma technique was developed to enhance the wettability of the GNWs, and the strength of the sensor's oxidation response depended on the concentration of lactate. First, in order to eliminate interference from other substances, biosensors were primarily tested in deionized water and displayed good electrochemical reversibility at different scan rates (20-100 mV s(-1)), a large index range (1.0 mu M to 10.0mM) and a low detection limit (1.0 mu M) for lactate. Next, these sensors were further examined in phosphate buffer solution (to mimick human body fluids), and still exhibited high sensitivity, stability and flexibility. These results show that the GNW-based lactate biosensors possess important potential for application in clinical analysis, sports medicine and the food industry. |
| 资助项目 | NSFC[11404329] ; NSFC[61504148] ; NSFC[51402291] ; National High-tech R&D Program of China (863 Program)[2015AA034801] ; National Key Basic Research Development Program ( 973 Program) of China[2014CB541606] ; CAS Western Light Program ; Natural Science Foundation Project of CQ CSTC[Cstc2014jcyjjq50004] ; Chongqing Research Program of Basic Research and Frontier Technology[Cstc2015jcyjA50018] ; Basic Scientific Research Program of Chongqing Science and Technology Commission[Cstc2016jcyjA0314] |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000405474500001 |
| 出版者 | IOP PUBLISHING LTD |
| 源URL | [http://172.16.51.4:88/handle/2HOD01W0/177]  |
| 专题 | 微纳制造与系统集成研究中心 |
| 通讯作者 | Sun, Tai; Feng, Hua; Wei, Dapeng |
| 作者单位 | 1.Third Mil Med Univ, Southwest Hosp, Dept Neurosurg, Chongqing 400038, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing Key Lab Multi Scale Mfg Technol, Chongqing 400714, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Qianwei,Sun, Tai,Song, Xuefen,et al. Flexible electrochemical biosensors based on graphene nanowalls for the real-time measurement of lactate[J]. NANOTECHNOLOGY,2017,28(31):8. |
| APA | Chen, Qianwei.,Sun, Tai.,Song, Xuefen.,Ran, Qincui.,Yu, Chongsheng.,...&Wei, Dapeng.(2017).Flexible electrochemical biosensors based on graphene nanowalls for the real-time measurement of lactate.NANOTECHNOLOGY,28(31),8. |
| MLA | Chen, Qianwei,et al."Flexible electrochemical biosensors based on graphene nanowalls for the real-time measurement of lactate".NANOTECHNOLOGY 28.31(2017):8. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。