In vivo characterization of hair and skin derived carbon quantum dots with high quantum yield as long-term bioprobes in zebrafish
文献类型：期刊论文
| 作者 | Zhang, Jing-Hui1,2; Niu, Aping2 ; Li, Jing1; Fu, Jian-Wei1; Xu, Qun1; Pei, De-Sheng2
|
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016-11-25 |
| 卷号 | 6页码:12 |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep37860 |
| 通讯作者 | Xu, Q (reprint author), Zhengzhou Univ, Coll Mat Sci & Engn, Zhengzhou 450052, Peoples R China. ; Pei, DS (reprint author), Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China. |
| 英文摘要 | Carbon quantum dots (CDs) were widely investigated because of their tunable fluorescence properties and low toxicity. However, so far there have been no reports on in vivo functional studies of hair and skin derived CDs. Here, hair derived CDs (HCDs) and skin derived CDs (SCDs) were produced by using human hair and pig skin as precursors. The quantum yields (QYs) of HCDs and SCDs were quite high, compared to citric acid derived CDs (CCDs). HCDs and SCDs possess optimal photostability, hypotoxicity and biocompatibility in zebrafish, indicating that HCDs and SCDs possess the capacity of being used as fluorescence probes for in vivo biological imaging. The long-time observation for fluorescence alternation of CDs in zebrafish and the quenching assay of CDs by ATP, NADH and Fe3+ ions demonstrated that the decaying process of CDs in vivo might be induced by the synergistic effect of the metabolism process. All results indicated that large batches and high QYs of CDs can be acquired by employing natural and nontoxic hair and skin as precursors. To our knowledge, this is the first time to report SCDs, in vivo comparative studies of HCDs, SCDs and CCDs as bioprobes, and explore their mechanism of photostability in zebrafish. |
| URL标识 | 查看原文 |
| 资助项目 | Key Application and Development Program of Chongqing Science and Technology Commission[cstc2014yykfC20004] ; Application and Development Program of Science and Technology Commission of Beibei District, Chongqing[2015-07] ; Scientific Research Starting Foundation for Returned Overseas Chinese Scholars from Ministry of Education ; National Technology Foundation for Selected Overseas Chinese Scholar of Chongqing Human Resources and Social Security Bureau, China |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000388473200001 |
| 出版者 | NATURE PUBLISHING GROUP |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/3094]  |
| 专题 | 环境与健康研究中心 |
| 通讯作者 | Xu, Qun; Pei, De-Sheng |
| 作者单位 | 1.Zhengzhou Univ, Coll Mat Sci & Engn, Zhengzhou 450052, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Jing-Hui,Niu, Aping,Li, Jing,et al. In vivo characterization of hair and skin derived carbon quantum dots with high quantum yield as long-term bioprobes in zebrafish[J]. SCIENTIFIC REPORTS,2016,6:12. |
| APA | Zhang, Jing-Hui,Niu, Aping,Li, Jing,Fu, Jian-Wei,Xu, Qun,&Pei, De-Sheng.(2016).In vivo characterization of hair and skin derived carbon quantum dots with high quantum yield as long-term bioprobes in zebrafish.SCIENTIFIC REPORTS,6,12. |
| MLA | Zhang, Jing-Hui,et al."In vivo characterization of hair and skin derived carbon quantum dots with high quantum yield as long-term bioprobes in zebrafish".SCIENTIFIC REPORTS 6(2016):12. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。