White matter reduction in patients with schizophrenia as revealed by voxel-based morphometry: An activation likelihood estimation meta-analysis
文献类型：期刊论文
| 作者 | Di, Xin1,3; Chan, Raymond C. K.1,2 ; Gong, Qi-yong4; R. C. K. Chan
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| 刊名 | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
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| 出版日期 | 2009-11-13 |
| 卷号 | 33期号:8页码:1390-1394 |
| 关键词 | Activation likelihood estimation Meta-analysis Schizophrenia Voxel-based morphology White matter |
| ISSN号 | 0278-5846 |
| 文献子类 | Review |
| 英文摘要 | Schizophrenia is thought to be a mental disorder caused by the disconnection of brain regions. Cumulative evidence of white matter deficit in patients with schizophrenia has been reported using voxel-based morphometry (VBM), but these studies have not been quantitatively reviewed. In the study reported herein, we used activation likelihood estimation (ALE) analysis to quantitatively estimate focal white matter abnormalities in patients with schizophrenia. Seventeen studies that compared the white matter deficit of patients with schizophrenia and healthy controls were ascertained. The frontal white matter regions and internal capsule revealed consistent white matter reduction in patient groups relative to healthy controls, suggesting a clear focal white matter deficit in patients with schizophrenia. These results support the macro-circuit theory of white matter change in schizophrenia.; Schizophrenia is thought to be a mental disorder caused by the disconnection of brain regions. Cumulative evidence of white matter deficit in patients with schizophrenia has been reported using voxel-based morphometry (VBM), but these studies have not been quantitatively reviewed. In the study reported herein, we used activation likelihood estimation (ALE) analysis to quantitatively estimate focal white matter abnormalities in patients with schizophrenia. Seventeen studies that compared the white matter deficit of patients with schizophrenia and healthy controls were ascertained. The frontal white matter regions and internal capsule revealed consistent white matter reduction in patient groups relative to healthy controls, suggesting a clear focal white matter deficit in patients with schizophrenia. These results support the macro-circuit theory of white matter change in schizophrenia. (C) 2009 Elsevier Inc. All rights reserved. |
| 学科主题 | 精神病学 ; 认知神经科学 |
| 语种 | 英语 |
| WOS记录号 | WOS:000272767100011 |
| 公开日期 | 2011-08-22 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/5837]  |
| 专题 | 心理研究所_中国科学院心理研究所回溯数据库(1956-2010) |
| 通讯作者 | R. C. K. Chan |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 10010, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 10010, Peoples R China 3.Sun Yat Sen Univ, Dept Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Guangzhou, Guangdong, Peoples R China 4.Sichuan Univ, Huaxi MR Res Ctr, Dept Radiol, W China Hosp,W China Sch Med, Chengdu 610064, Peoples R China |
| 推荐引用方式 GB/T 7714 | Di, Xin,Chan, Raymond C. K.,Gong, Qi-yong,et al. White matter reduction in patients with schizophrenia as revealed by voxel-based morphometry: An activation likelihood estimation meta-analysis[J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,2009,33(8):1390-1394. |
| APA | Di, Xin,Chan, Raymond C. K.,Gong, Qi-yong,&R. C. K. Chan.(2009).White matter reduction in patients with schizophrenia as revealed by voxel-based morphometry: An activation likelihood estimation meta-analysis.PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,33(8),1390-1394. |
| MLA | Di, Xin,et al."White matter reduction in patients with schizophrenia as revealed by voxel-based morphometry: An activation likelihood estimation meta-analysis".PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 33.8(2009):1390-1394. |
入库方式： OAI收割
来源：心理研究所
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