Cerebral and functional adaptation with chronic hypoxia exposure: A multi-modal MRI study
文献类型：期刊论文
| 作者 | Yan, Xiaodan2,3; Zhang, Jiaxing1,2; Shi, Jinfu2; Gong, Qiyong4; Weng, Xuchu2 ; Weng XC(翁旭初)
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| 刊名 | BRAIN RESEARCH
 |
| 出版日期 | 2010-08-12 |
| 卷号 | 1348期号:1348页码:21-29 |
| 关键词 | Hypoxia VBM DTI ReHo Resting state BOLD fMRI Plasticity |
| ISSN号 | 0006-8993 |
| 文献子类 | Article |
| 英文摘要 | The current study obtained multi-modal MRI data from 28 immigrant high altitude (HA) young adults who were born and grew up at Qinghai-Tibetan plateau matched with 28 matched sea level (SL) controls. We compared their regional gray matter volumes (VBM) and white matter quality (DAI FA values) as well as resting state brain activity (Regional Homogeneity (ReHo) of BOLD-fMRI). We found that HA residents showed decreased gray matter volume at bilateral anterior insula, bilateral prefrontal cortex, the left precentral, the left cingulate and the right lingual cortex; accompanied by changed FA and ReHo values in relevant and other regions. The resting state activity at the hippocampus and the right insula were increasing with SL relocation. The HA subjects performed worse on a series of working memory tasks, with the ReHo values of several regions as significant predictors of their performance. This study demonstrated the cerebral and functional modifications with chronic high altitude hypoxia. (C) 2010 Elsevier B.V. All rights reserved. |
| 学科主题 | 认知心理学 |
| 资助项目 | 二室翁旭初课题组 |
| 语种 | 英语 |
| WOS记录号 | WOS:000281222400003 |
| 公开日期 | 2011-11-14 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/6965]  |
| 专题 | 心理研究所_中国科学院心理研究所回溯数据库(1956-2010) |
| 通讯作者 | Weng XC(翁旭初) |
| 作者单位 | 1.Xiamen Univ, Coll Med, Dept Physiol, Xiamen 361005, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Lab Higher Brain Funct, Beijing 100101, Peoples R China 3.NYU, Langone Med Ctr, New York, NY 10016 USA 4.Sichuan Univ, W China Hosp, Huaxi Magnet Resonance Res Ctr, Chengdu 610041, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Xiaodan,Zhang, Jiaxing,Shi, Jinfu,et al. Cerebral and functional adaptation with chronic hypoxia exposure: A multi-modal MRI study[J]. BRAIN RESEARCH,2010,1348(1348):21-29. |
| APA | Yan, Xiaodan,Zhang, Jiaxing,Shi, Jinfu,Gong, Qiyong,Weng, Xuchu,&翁旭初.(2010).Cerebral and functional adaptation with chronic hypoxia exposure: A multi-modal MRI study.BRAIN RESEARCH,1348(1348),21-29. |
| MLA | Yan, Xiaodan,et al."Cerebral and functional adaptation with chronic hypoxia exposure: A multi-modal MRI study".BRAIN RESEARCH 1348.1348(2010):21-29. |
入库方式： OAI收割
来源：心理研究所
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