MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation.
文献类型：期刊论文
| 作者 | Hou HB; Zhao FQ; Zhou LL; Zhu EL; Teng HJ; Li XK; Bao QY; Wu JY; Sun ZS(孙中生) ; Jinyu Wu
|
| 刊名 | Nucleic Acids Research
 |
| 出版日期 | 2010 |
| 卷号 | 38期号:5页码:W732–W736 |
| ISSN号 | 0305-1048 |
| 英文摘要 | New sequencing technologies, such as Roche 454, ABI SOLiD and Illumina, have been increasingly developed at an astounding pace with the advantages of high throughput, reduced time and cost. To satisfy the impending need for deciphering the large-scale data generated from next-generation sequencing, an integrated software MagicViewer is developed to easily visualize short read mapping, identify and annotate genetic variation based on the reference genome. MagicViewer provides a user-friendly environment in which large-scale short reads can be displayed in a zoomable interface under user-defined color scheme through an operating system-independent manner. Meanwhile, it also holds a versatile computational pipeline for genetic variation detection, filtration, annotation and visualization, providing details of search option, functional classification, subset selection, sequence association and primer design. In conclusion, MagicViewer is a sophisticated assembly visualization and genetic variation annotation tool for next-generation sequencing data, which can be widely used in a variety of sequencing-based researches, including genome re-sequencing and transcriptome studies. MagicViewer is freely available at http://bioinformatics.zj.cn/magicviewer/. |
| 学科主题 | 生理心理学/生物心理学 |
| 资助项目 | 一室原孙中生课题组 |
| 语种 | 英语 |
| 公开日期 | 2011-12-02 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/7247]  |
| 专题 | 心理研究所_中国科学院心理研究所回溯数据库(1956-2010) |
| 通讯作者 | Sun ZS(孙中生); Jinyu Wu |
| 推荐引用方式 GB/T 7714 | Hou HB,Zhao FQ,Zhou LL,et al. MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation.[J]. Nucleic Acids Research,2010,38(5):W732–W736. |
| APA | Hou HB.,Zhao FQ.,Zhou LL.,Zhu EL.,Teng HJ.,...&Jinyu Wu.(2010).MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation..Nucleic Acids Research,38(5),W732–W736. |
| MLA | Hou HB,et al."MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation.".Nucleic Acids Research 38.5(2010):W732–W736. |
入库方式： OAI收割
来源：心理研究所
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