We employed a boundary paradigm to investigate how Chinese two-character compounds (i.e., compound words) are processed during reading. The first character of the compound was an ambiguous morpheme that had a dominant and subordinate meaning. In Experiment 1, there were three previews of the second character: identical to the target character; the preview provided subordinate biasing information (the subordinate condition); the preview provided dominant biasing information (the dominant condition). An invisible boundary was inserted between the two characters. We found that gaze durations and go-past times on the compounds were longer in the subordinate condition than those in the dominant or identical conditions. In Experiment 2, the semantic similarity between target and preview words in the dominant condition was manipulated to determine whether the differences in fixation durations in Experiment 1 resulted from the semantic similarity between the preview and target words. There were significant fixation duration differences on the target word between the dominant and subordinate conditions only when the preview and target words were semantically related. This finding indicated that the whole-word meaning plays an important role in processing Chinese compounds and that the whole-word access route is the principal processing route in reading two-character compounds in Chinese.